STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (302 aa)    
Predicted Functional Partners:
Ava_0783
Homoserine dehydrogenase.
  
 0.995
Ava_3117
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.984
Ava_4952
L-threonine synthase.
 
 
 0.984
Ava_3052
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.880
Ava_4156
Cystathionine beta-synthase.
     
 0.832
Ava_1668
Serine O-acetyltransferase.
     
 0.827
Ava_3953
Serine O-acetyltransferase.
     
 0.827
Ava_5017
Serine O-acetyltransferase.
     
 0.827
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.800
Ava_3642
Aspartate kinase.
  
 
 0.799
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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