STRINGSTRING
PG_0025 protein (Porphyromonas gingivalis W83) - STRING interaction network
"PG_0025" - Fumarylacetoacetate hydrolase in Porphyromonas gingivalis W83
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PG_0025Fumarylacetoacetate hydrolase (219 aa)    
Predicted Functional Partners:
pruA
Delta-1-pyrroline-5-carboxylate dehydrogenase (543 aa)
 
  0.843
sucD
Succinate-semialdehyde dehydrogenase (451 aa)
   
  0.843
fumB
Fumarate hydratase class I, anaerobic (548 aa)
       
    0.812
4hbD
NAD-dependent 4-hydroxybutyrate dehydrogenase (371 aa)
   
 
    0.789
ilvE
Branched-chain amino acid aminotransferase (339 aa)
       
    0.787
pdhD
Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase (449 aa)
     
 
    0.786
dnaN
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (377 aa)
     
      0.687
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state (218 aa)
              0.666
PG_0026
Hypothetical protein (1123 aa)
              0.665
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (162 aa)
              0.583
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
Server load: low (8%) [HD]