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prfC protein (Porphyromonas gingivalis W83) - STRING interaction network
"prfC" - Peptide chain release factor 3 in Porphyromonas gingivalis W83
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (526 aa)    
Predicted Functional Partners:
PG_0204
Hypothetical protein (81 aa)
              0.859
PG_0199
TatD family protein (237 aa)
              0.709
PG_0200
Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane (76 aa)
   
        0.709
PG_0203
Hypothetical protein (235 aa)
              0.689
PG_0202
uroporphyrinogen-III synthase (248 aa)
              0.689
rnpA
Ribonuclease P; RNaseP catalyzes the removal of the 5’-leader sequence from pre-tRNA to produce the mature 5’-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5’-leader sequence and broadening the substrate specificity of the ribozyme (137 aa)
              0.689
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (340 aa)
         
  0.642
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (361 aa)
     
 
  0.526
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (506 aa)
   
   
  0.512
polA
DNA polymerase type I (926 aa)
         
  0.509
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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