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mtn protein (Porphyromonas gingivalis W83) - STRING interaction network
"mtn" - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in Porphyromonas gingivalis W83
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
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mtn5’-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5’-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5’-methylthioribose and S-ribosylhomocysteine, respectively (228 aa)    
Predicted Functional Partners:
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (159 aa)
 
   
  0.999
PG_0496
Hypothetical protein (30 aa)
              0.859
hpt
Hypoxanthine phosphoribosyltransferase (178 aa)
     
 
    0.793
PG_0171
5’-nucleotidase (590 aa)
   
   
    0.777
PG_0936
Xanthine/uracil permease (433 aa)
       
    0.764
PG_1730
O-methyltransferase (216 aa)
       
    0.764
fabD
Malonyl CoA-ACP transacylase (293 aa)
   
        0.662
PG_1097
Putative bifunctional UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase/alanine racemase (823 aa)
   
   
  0.586
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5’-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (193 aa)
       
  0.575
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (429 aa)
     
 
  0.528
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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