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groS protein (Porphyromonas gingivalis W83) - STRING interaction network
"groS" - Chaperonin, 10 kDa in Porphyromonas gingivalis W83
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
groSChaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (89 aa)    
Predicted Functional Partners:
groL
Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (545 aa)
 
  0.999
dnaK
dnaK protein; Acts as a chaperone (640 aa)
   
 
  0.955
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity (684 aa)
     
 
  0.930
grpE
grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] (194 aa)
 
 
  0.920
guaB
Inosine 5-monophosphate dehydrogenase (498 aa)
   
   
  0.863
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes (101 aa)
     
   
  0.837
tuf
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (395 aa)
     
 
  0.834
sodB
Superoxide dismutase, Fe-Mn; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (191 aa)
   
 
  0.832
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation (125 aa)
     
   
  0.829
clpB
clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity) (863 aa)
   
 
  0.816
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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