STRINGSTRING
panB protein (Porphyromonas gingivalis W83) - STRING interaction network
"panB" - 3-methyl-2-oxobutanoate hydroxymethyltransferase in Porphyromonas gingivalis W83
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (273 aa)    
Predicted Functional Partners:
panE
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (314 aa)
       
  0.989
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (281 aa)
 
 
  0.985
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (506 aa)
              0.822
panD
Aspartate-1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (118 aa)
   
   
  0.818
ilvE
Branched-chain amino acid aminotransferase (339 aa)
       
  0.764
folC
Folylpolyglutamate synthase (429 aa)
         
  0.711
PG_1504
NAD dependent protein (328 aa)
       
    0.690
yadS
yadS protein (210 aa)
              0.686
rpe
Ribulose-phosphate 3-epimerase (218 aa)
           
  0.677
trpG
Anthranilate synthase component II (198 aa)
           
  0.611
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
Server load: low (9%) [HD]