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folD protein (Porphyromonas gingivalis W83) - STRING interaction network
"folD" - Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase in Porphyromonas gingivalis W83
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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folDMethylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (296 aa)    
Predicted Functional Partners:
fhs
Formate--tetrahydrofolate ligase (555 aa)
 
  0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (193 aa)
 
 
  0.996
PG_1854
5-formyltetrahydrofolate cyclo-ligase (185 aa)
 
  0.992
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (426 aa)
   
  0.977
gcvP
Glycine dehydrogenase (955 aa)
   
 
  0.971
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine (362 aa)
   
 
  0.962
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (508 aa)
   
 
  0.952
purD
Phosphoribosylamine--glycine ligase (431 aa)
   
 
  0.950
folC
Folylpolyglutamate synthase (429 aa)
 
 
  0.928
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (267 aa)
   
 
  0.906
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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