STRINGSTRING
purB protein (Porphyromonas gingivalis W83) - STRING interaction network
"purB" - Adenylosuccinate lyase in Porphyromonas gingivalis W83
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purBAdenylosuccinate lyase (447 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (423 aa)
 
 
  0.998
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (313 aa)
   
  0.998
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (508 aa)
   
  0.997
purD
Phosphoribosylamine--glycine ligase (431 aa)
   
  0.991
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (194 aa)
   
  0.986
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1234 aa)
 
 
  0.980
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (193 aa)
   
  0.966
PG_0075
Phosphoribosylformylglycinamidine cyclo-ligase (413 aa)
   
 
  0.947
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (506 aa)
   
   
  0.930
guaB
Inosine 5-monophosphate dehydrogenase (498 aa)
   
   
  0.911
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
Server load: low (10%) [HD]