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alaS protein (Porphyromonas gingivalis W83) - STRING interaction network
"alaS" - alanyl-tRNA synthetase in Porphyromonas gingivalis W83
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (876 aa)    
Predicted Functional Partners:
pheT
phenylalanyl-tRNA synthetase subunit beta (819 aa)
 
 
  0.975
leuS
leucyl-tRNA synthetase (925 aa)
   
 
  0.936
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile) (1137 aa)
   
 
  0.928
aroB
3-dehydroquinate synthase (353 aa)
   
 
  0.928
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (680 aa)
   
 
  0.907
hisS
histidyl-tRNA synthetase (454 aa)
   
   
  0.886
PG_1745
Phosphoribulokinase (529 aa)
   
 
  0.885
thrS
threonyl-tRNA synthetase (653 aa)
   
 
  0.881
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (876 aa)
 
   
  0.875
cysS
cysteinyl-tRNA synthetase (490 aa)
 
   
  0.872
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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