STRINGSTRING
lipB protein (Porphyromonas gingivalis W83) - STRING interaction network
"lipB" - Lipoate-protein ligase B in Porphyromonas gingivalis W83
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (492 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (282 aa)
 
  0.999
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (78 aa)
   
  0.917
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (126 aa)
   
  0.875
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation (338 aa)
   
        0.856
PG_1341
Hypothetical protein (184 aa)
              0.773
gcvP
Glycine dehydrogenase (955 aa)
   
   
  0.768
pdhD
Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase (449 aa)
 
   
  0.760
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3’- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA (304 aa)
     
 
  0.744
polA
DNA polymerase type I (926 aa)
   
   
  0.634
rlmH
rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (157 aa)
   
        0.592
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
Server load: low (2%) [HD]