STRINGSTRING
topB-2 protein (Porphyromonas gingivalis W83) - STRING interaction network
"topB-2" - DNA topoisomerase III in Porphyromonas gingivalis W83
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topB-2DNA topoisomerase III (697 aa)    
Predicted Functional Partners:
recQ-1
ATP-dependent DNA helicase RecQ (725 aa)
 
  0.954
recQ-2
ATP-dependent DNA helicase RecQ (655 aa)
 
  0.952
PG_1496
Hypothetical protein (91 aa)
 
          0.933
polA
DNA polymerase type I (926 aa)
   
  0.914
PG_0932
DNA polymerase III, delta prime subunit (416 aa)
   
  0.901
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (340 aa)
   
  0.877
umuC
umuC protein (432 aa)
   
  0.836
dnaN
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (377 aa)
   
  0.833
PG_1494
Hypothetical protein (437 aa)
 
          0.769
PG_0847
Hypothetical protein (526 aa)
 
          0.768
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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