STRINGSTRING
folK protein (Porphyromonas gingivalis W83) - STRING interaction network
"folK" - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase in Porphyromonas gingivalis W83
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folK2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (149 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase (281 aa)
 
  0.999
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (117 aa)
 
 
  0.995
folC
Folylpolyglutamate synthase (429 aa)
 
 
  0.934
PG_1540
S-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (350 aa)
   
        0.911
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (162 aa)
 
   
  0.882
prtC
Collagenase; Expresses collagenase activity. Hydrolyzes type I collagen. May play a role in virulence (By similarity) (414 aa)
   
        0.833
PG_1694
Hypothetical protein (364 aa)
     
 
    0.782
folE
GTP cyclohydrolase I (193 aa)
 
   
  0.739
trpG
Anthranilate synthase component II (198 aa)
 
   
  0.714
ilvE
Branched-chain amino acid aminotransferase (339 aa)
       
  0.659
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
Server load: low (9%) [HD]