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prtC protein (Porphyromonas gingivalis W83) - STRING interaction network
"prtC" - Collagenase in Porphyromonas gingivalis W83
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
prtCCollagenase; Expresses collagenase activity. Hydrolyzes type I collagen. May play a role in virulence (By similarity) (414 aa)    
Predicted Functional Partners:
PG_1540
S-adenosylmethionine-tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (350 aa)
     
      0.853
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (149 aa)
   
        0.833
PG_1543
Thioesterase (139 aa)
              0.699
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (595 aa)
   
 
  0.603
ligA
NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (669 aa)
         
  0.582
purE
Phosphoribosylaminoimidazole carboxylase, PurE protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (168 aa)
   
   
  0.558
pheT
phenylalanyl-tRNA synthetase subunit beta (819 aa)
   
        0.545
fimA
Fimbrilin; Fimbrillin is the structural subunit of the fimbriae, that are filamentous appendages on the cell surface. Fimbriae of P.gingivalis are recognized as a major virulence factor as they mediate cell adhesion and play an important role in invasion of periodontal tissues (By similarity) (388 aa)
           
  0.529
tpr
Thiol protease; Thiol protease. Probably an important virulence factor (481 aa)
           
  0.529
rgp2
Arginine-specific cysteine proteinase; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5 (By similarity) (736 aa)
           
  0.529
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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