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gcvT protein (Porphyromonas gingivalis W83) - STRING interaction network
"gcvT" - Glycine cleavage system T protein in Porphyromonas gingivalis W83
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine (362 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (955 aa)
 
  0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (126 aa)
 
  0.999
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (426 aa)
 
  0.996
folD
Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (296 aa)
   
 
  0.962
pdhD
Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase (449 aa)
 
 
  0.928
PG_1210
M24 family peptidase (595 aa)
   
  0.866
PG_0889
M24 family peptidase (398 aa)
   
  0.866
PG_0474
Low-specificity L-threonine aldolase (345 aa)
     
    0.863
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (267 aa)
   
  0.859
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (162 aa)
   
 
  0.834
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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