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nth protein (Porphyromonas gingivalis W83) - STRING interaction network
"nth" - Endonuclease III in Porphyromonas gingivalis W83
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (224 aa)    
Predicted Functional Partners:
xth
Exodeoxyribonuclease III (254 aa)
 
 
  0.991
pheS
phenylalanyl-tRNA synthetase subunit alpha (340 aa)
     
      0.834
polA
DNA polymerase type I (926 aa)
 
 
  0.769
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (680 aa)
   
   
  0.748
PG_1773
PAP2 superfamily protein (445 aa)
              0.662
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (340 aa)
   
 
  0.648
der
GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis (437 aa)
   
   
  0.633
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (256 aa)
         
  0.614
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (1122 aa)
 
 
 
  0.608
PG_1770
Hypothetical protein (225 aa)
              0.591
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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