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metK protein (Porphyromonas gingivalis W83) - STRING interaction network
"metK" - S-adenosylmethionine synthase in Porphyromonas gingivalis W83
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (429 aa)    
Predicted Functional Partners:
rfbD
dTDP-4-dehydrorhamnose reductase (285 aa)
     
  0.952
rlmN
Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs (341 aa)
     
    0.878
PG_1327
Aminotransferase (436 aa)
   
  0.823
rplI
Ribosomal protein L9; Binds to the 23S rRNA (179 aa)
       
  0.820
PG_1730
O-methyltransferase (216 aa)
   
 
    0.811
groL
Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (545 aa)
   
 
  0.811
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (162 aa)
            0.810
msrA
Peptide methionine sulfoxide reductase (352 aa)
   
 
  0.792
mgl
Methionine gamma-lyase; Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia; methanethiol (methyl mercaptan) is considered to be one of the main causes of oral malodor and may also play a role in the pathogenicity of P.gingivalis in periodontal disease (PubMed-11083813). Is also able to catalyze the alpha,gamma-elimination of L-homocysteine (By similarity) (393 aa)
   
 
  0.791
kamE
D-lysine 5,6-aminomutase subunit beta (263 aa)
       
    0.781
Your Current Organism:
Porphyromonas gingivalis W83
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
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