STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase, putative; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa)    
Predicted Functional Partners:
PG_1745
Phosphoribulokinase family protein; Similar to SP:P13467, SP:P16155, SP:P23732, SP:P17451, SP:P19542, SP:P06597, SP:P23114, SP:P23421, GB:X16007, SP:P08780, GB:J03813, GB:L35605, GB:L35606, GB:M14738, GB:M17342, GB:M33635, GB:M33636, GB:M35099, GB:M36533, GB:M58938, GB:X55700, GB:X62921, PID:1321799, PID:2076876, SP:P13467, SP:P16155, SP:P23732, SP:P17451, SP:P19542, SP:P06597, SP:P23114, SP:P23421, GB:X52080, SP:P08780, GB:J03813, GB:L35605, GB:L35606, GB:M14738, GB:M17342, GB:M33635, GB:M33636, GB:M35099, GB:M36533, GB:M58938, GB:X55700, GB:X62921, PID:1321799, PID:2076876, SP:P13467 [...]
  
 0.962
udk
Uridine kinase.
  
 0.958
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.956
pyrF
Orotidine 5'-monophosphate decarboxylase; Identified by match to TIGR protein family HMM TIGR01740; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.936
PG_1371
Phosphorylase family protein.
  
  
 0.931
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.930
PG_0558
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.921
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.908
prtQ
Protease.
  
    0.808
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.737
Your Current Organism:
Porphyromonas gingivalis
NCBI taxonomy Id: 242619
Other names: P. gingivalis W83, Porphyromonas gingivalis W83, Porphyromonas gingivalis str. W83, Porphyromonas gingivalis strain W83
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.