node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PG_0026 | PG_0534 | PG_0026 | PG_0534 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.773 |
PG_0026 | PG_0602 | PG_0026 | PG_0602 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.788 |
PG_0026 | hagA | PG_0026 | PG_1837 | Hypothetical protein; Identified by Glimmer2; putative. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.553 |
PG_0026 | porT | PG_0026 | PG_0751 | Hypothetical protein; Identified by Glimmer2; putative. | porT protein. | 0.816 |
PG_0093 | hagA | PG_0093 | PG_1837 | HlyD family secretion protein. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.633 |
PG_0283 | hagA | PG_0283 | PG_1837 | Efflux transporter, MFP component, RND family; Similar to GB:D28503, PID:556484, and SP:Q59295; identified by sequence similarity; putative. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.564 |
PG_0534 | PG_0026 | PG_0534 | PG_0026 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.773 |
PG_0534 | PG_0602 | PG_0534 | PG_0602 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.774 |
PG_0534 | hagA | PG_0534 | PG_1837 | Hypothetical protein; Identified by Glimmer2; putative. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.543 |
PG_0534 | porT | PG_0534 | PG_0751 | Hypothetical protein; Identified by Glimmer2; putative. | porT protein. | 0.724 |
PG_0602 | PG_0026 | PG_0602 | PG_0026 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.788 |
PG_0602 | PG_0534 | PG_0602 | PG_0534 | Hypothetical protein; Identified by Glimmer2; putative. | Hypothetical protein; Identified by Glimmer2; putative. | 0.774 |
PG_0602 | hagA | PG_0602 | PG_1837 | Hypothetical protein; Identified by Glimmer2; putative. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.610 |
PG_0602 | hagE | PG_0602 | PG_2024 | Hypothetical protein; Identified by Glimmer2; putative. | Hemagglutinin protein HagE; Cleaves human complement component C3. May enable P.gingivalis to evade complement-mediated killing during the immune response. Plays an important role in soft tissue infections and is a virulence factor; Belongs to the peptidase C25 family. | 0.484 |
PG_0602 | porT | PG_0602 | PG_0751 | Hypothetical protein; Identified by Glimmer2; putative. | porT protein. | 0.634 |
PG_1424 | hagA | PG_1424 | PG_1837 | Peptidylarginine deiminase; Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.571 |
PG_1424 | hagE | PG_1424 | PG_2024 | Peptidylarginine deiminase; Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. | Hemagglutinin protein HagE; Cleaves human complement component C3. May enable P.gingivalis to evade complement-mediated killing during the immune response. Plays an important role in soft tissue infections and is a virulence factor; Belongs to the peptidase C25 family. | 0.703 |
PG_2174 | hagA | PG_2174 | PG_1837 | Hypothetical protein; Identified by Glimmer2; putative. | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.729 |
PG_2174 | hagE | PG_2174 | PG_2024 | Hypothetical protein; Identified by Glimmer2; putative. | Hemagglutinin protein HagE; Cleaves human complement component C3. May enable P.gingivalis to evade complement-mediated killing during the immune response. Plays an important role in soft tissue infections and is a virulence factor; Belongs to the peptidase C25 family. | 0.423 |
fimA | hagA | PG_2132 | PG_1837 | Fimbrilin; Structural subunit of the major fimbriae. These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome. They play an important role in the invasion of periodontal tissues. Fimbriae and their constituents are major virulence factors. FimA proteins from different strains have highly divergent sequences, and this has been used for classification. The sequence-based classification correlates with pathogenicity; Belongs to the bacteroidetes fimbrillin superfamil [...] | Hemagglutinin protein HagA; Agglutinates erythrocytes. | 0.550 |