STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1066Hypothetical protein. (820 aa)    
Predicted Functional Partners:
RB12506
Probable anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PMID: 9266669 best DB hits: BLAST: ddbj:BAB05255.1; (AP001512) anti-sigma F factor antagonist (stage; E=0.003 pir:S75220; hypothetical protein slr1912 - Synechocystis sp. (strain; E=0.024 COG: BH1536; COG1366 Anti-anti-sigma regulatory factor (antagonist of; E=3e-04 PFAM: PF01740; STAS domain; E=4.9e-06.
  
 
 0.881
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
  
  
 0.866
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
  
  
 0.864
RB1764
Conserved hypothetical protein-putative transcription regulator; Best DB hits: BLAST: gb:AAG59798.1; AF292097_4 (AF292097) SenB [Leptospira interrogans]; E=4e-06 gb:AAC23717.1; (AF031161) transcriptional activator [Pseudomonas; E=0.004 pir:C82379; response regulator VCA1086 [imported] - Vibrio cholerae; E=0.005 COG: VCA1086_2; COG2208 Serine phosphatase RsbU, regulator of sigma; E=5e-04 TP0995; COG0664 cAMP-binding domains - Catabolite gene activator and; E=0.002 PFAM: PF00072; Response regulator receiver doma; E=0.29 PF02518; Histidine kinase-, DNA gyrase B-; E=0.65.
  
 
 0.862
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
  
  
 0.822
RB159
PMID: 11406410 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-63 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=8e-62 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-53 PFAM: PF00989; PAS domain; E=5.9e-05 PF00512; His Kinase A (phosphoacceptor); E=4.2e-24 PF02518; Histidine kinase-, DNA gyrase B; E=4.1e-43.
  
  
 0.822
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
   
    0.792
fliM
Flagellar motor switch protein fliM; PMID: 96345631 PMID: 8755894 best DB hits: BLAST: swissprot:P74927; FLIM_TREPA FLAGELLAR MOTOR SWITCH PROTEIN FLIM; E=7e-47 swissprot:Q57511; FLIM_BORBU FLAGELLAR MOTOR SWITCH PROTEIN FLIM; E=5e-46 ddbj:BAB06165.1; (AP001515) flagellar motor switch protein; E=3e-44 COG: TP0721; COG1868 Flagellar motor switch protein; E=7e-48 PFAM: PF02154; Flagellar motor switch protein FliM; E=1.3e-68 PF01052; Surface presentation of antigens (S; E=0.19.
  
    0.755
mqnE
Conserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
   
    0.751
mqnC
Conserved hypothetical protein-putative oxidoreductase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
   
    0.751
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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