STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (243 aa)    
Predicted Functional Partners:
msrB
Peptide methionine sulfoxide reductase; PMID: 9278503 best DB hits: BLAST: pir:C81315; hypothetical protein Cj1112c [imported] - Campylobacter; E=9e-33 embl:CAB80845.1; (AL161501) putative protein [Arabidopsis; E=4e-27 gb:AAD03449.1; (AF118223) contains similarity to Methanobacterium; E=5e-27 COG: Cj1112c; COG0229 Conserved domain frequently associated with peptide; E=8e-34 VNG1404G; COG0229 Conserved domain frequently associated with; E=5e-19 XF0849; COG0229 Conserved domain frequently associated with peptide; E=2e-17 PFAM: PF01641; Domain of unknown function DUF25; E=3.7e-46.
 
 0.990
msrB-2
Probable peptide methionine sulfoxide reductase msrB; PMID: 97426617 PMID: 9278503 best DB hits: BLAST: swissprot:P39903; YEAA_ECOLI HYPOTHETICAL 15.5 KDA PROTEIN IN; E=5e-32 gb:AAG51964.1; AC024260_2 (AC024260) transcriptional regulator,; E=3e-31 ddbj:BAA15575.1; (D90821) F44E2.6 protein [Escherichia coli]; E=4e-30 COG: yeaA; COG0229 Conserved domain frequently associated with peptide; E=5e-33 HI1455_2; COG0229 Conserved domain frequently associated with; E=3e-29 BS_yppQ; COG0229 Conserved domain frequently associated with peptide; E=2e-28 PFAM: PF01641; Domain of unknown function DUF [...]
 
 0.990
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.883
RB11848
Hypothetical protein.
       0.596
hofF
General secretion pathway protein F-putative pilus protein; PMID: 1640836 PMID: 93174466 best DB hits: BLAST: gb:AAC70103.1; (AF074613) type II secretion protein [Escherichia; E=3e-15 pir:C82327; MSHA biogenesis protein MshG VC0406 [imported] - Vibrio; E=9e-15 gb:AAA96018.1; (U35009) MshG [Vibrio cholerae]; E=3e-13 COG: VC0406; COG1459 General secretory pathway protein F; E=8e-16 PFAM: PF00482; Bacterial type II secretion system p; E=3.4e-05.
       0.596
RB11845
Hypothetical protein.
       0.569
RB11846
Hypothetical protein.
       0.569
folE
GTP cyclohydrolase I; PMID: 1551827 PMID: 95352066 best DB hits: BLAST: swissprot:P19465; GCH1_BACSU GTP CYCLOHYDROLASE I (GTP-CH-I); E=1e-59 ddbj:BAB05365.1; (AP001512) GTP cyclohydrolase I [Bacillus; E=1e-57 swissprot:O06273; GCH1_MYCTU GTP CYCLOHYDROLASE I (GTP-CH-I); E=4e-53 COG: BS_mtrA; COG0302 GTP cyclohydrolase I; E=1e-60 PFAM: PF01227; GTP cyclohydrolase I; E=2.3e-110.
     
 0.519
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.458
cysN
cysN/cysC bifunctionyal enzyme; ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity; In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
  
 0.443
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.