node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RB12009 | phr | RB12009 | RB12007 | Hypothetical protein. | DNA photolyase; May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor (By similarity). | 0.773 |
RB12009 | proB | RB12009 | RB12013 | Hypothetical protein. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.527 |
RB12009 | xylB | RB12009 | RB12012 | Hypothetical protein. | Xylulose kinase; PMID: 9495747 best DB hits: BLAST: gb:AAC46146.1; (AF001974) xylulose kinase; XylB; E=1e-108 swissprot:P39211; XYLB_BACSU XYLULOSE KINASE (XYLULOKINASE); E=4e-79 ddbj:BAB06475.1; (AP001516) xylose kinase [Bacillus halodurans]; E=5e-76 COG: BS_xylB; COG1070 Sugar (pentulose and hexulose) kinases; E=4e-80 PAB2406; COG0554 Glycerol kinase; E=2e-31 APE0017; COG1070 Sugar (pentulose and hexulose) kinases; E=1e-27 PFAM: PF00370; FGGY family of carbohydrate kinas; E=6e-96 PF02782; FGGY family of carbohydrate kinas; E=7.6e-63. | 0.559 |
glyS | proB | RB10547 | RB12013 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.751 |
obg | proA | RB2630 | RB7359 | GTP-binding protein OBG; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.501 |
obg | proB | RB2630 | RB12013 | GTP-binding protein OBG; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.481 |
phr | RB12009 | RB12007 | RB12009 | DNA photolyase; May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor (By similarity). | Hypothetical protein. | 0.773 |
phr | proB | RB12007 | RB12013 | DNA photolyase; May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor (By similarity). | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.527 |
phr | xylB | RB12007 | RB12012 | DNA photolyase; May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor (By similarity). | Xylulose kinase; PMID: 9495747 best DB hits: BLAST: gb:AAC46146.1; (AF001974) xylulose kinase; XylB; E=1e-108 swissprot:P39211; XYLB_BACSU XYLULOSE KINASE (XYLULOKINASE); E=4e-79 ddbj:BAB06475.1; (AP001516) xylose kinase [Bacillus halodurans]; E=5e-76 COG: BS_xylB; COG1070 Sugar (pentulose and hexulose) kinases; E=4e-80 PAB2406; COG0554 Glycerol kinase; E=2e-31 APE0017; COG1070 Sugar (pentulose and hexulose) kinases; E=1e-27 PFAM: PF00370; FGGY family of carbohydrate kinas; E=6e-96 PF02782; FGGY family of carbohydrate kinas; E=7.6e-63. | 0.527 |
proA | obg | RB7359 | RB2630 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | GTP-binding protein OBG; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.501 |
proA | proB | RB7359 | RB12013 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.999 |
proA | proC | RB7359 | RB3891 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.818 |
proA | putA | RB7359 | RB8262 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | PMID: 96062224 best DB hits: BLAST: pir:H64526; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:B71980; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:C81297; proline dehydrogenase (EC 1.5.99.8); E=1e-180 COG: jhp0048_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-123 Cj1503c_1; COG0506 Proline dehydrogenase; E=2e-56 sll1561_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-51 PFAM: PF01619; Proline dehydrogenase; E=2e-36 PF00171; Aldehyde dehydrogenase family; E=0.0014; Belongs to the aldehyde dehydrogenase family. | 0.935 |
proA | ribA | RB7359 | RB12480 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.498 |
proB | RB12009 | RB12013 | RB12009 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Hypothetical protein. | 0.527 |
proB | glyS | RB12013 | RB10547 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.751 |
proB | obg | RB12013 | RB2630 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | GTP-binding protein OBG; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.481 |
proB | phr | RB12013 | RB12007 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | DNA photolyase; May have a photoreceptor function. Binds DNA; probably functions as a transcriptional repressor (By similarity). | 0.527 |
proB | proA | RB12013 | RB7359 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.999 |
proB | proC | RB12013 | RB3891 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.919 |