STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glcFPMID: 8606183 best DB hits: BLAST: pir:G75361; glycolate oxidase, iron-sulfur subunit - Deinococcus; E=1e-101 pir:S75231; (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) - Synechocystis; E=3e-62 ddbj:BAB05854.1; (AP001514) glycolate oxidase iron-sulfur subunit; E=2e-58 COG: DR1730; COG0247 Fe-S oxidoreductases; E=1e-102 PFAM: PF00037; 4Fe-4S binding domain; E=0.21 PF02754; Domain of unknown function (DUF2; E=4.9e-07. (444 aa)    
Predicted Functional Partners:
glcD
Glycolate oxidase subunit GlcD; PMID: 8606183 PMID: 11283302 best DB hits: BLAST: pir:E82977; glycolate oxidase subunit GlcD PA5355 [imported] -; E=1e-102 pir:S74338; glycolate oxidase chain glcD - Synechocystis sp. (strain; E=1e-101 swissprot:P52075; GLCD_ECOLI GLYCOLATE OXIDASE SUBUNIT GLCD; E=1e-99 COG: PA5355; COG0277 FAD/FMN-containing dehydrogenases; E=1e-103 PFAM: PF01565; FAD binding domain; E=2.7e-55 PF02913; FAD linked oxidases, C-terminal; E=7.9e-53.
 
 0.998
glcE
PMID: 8606183 best DB hits: BLAST: pir:H65083; glycolate oxidase subunits GlcE and GlcF - Escherichia; E=6e-23 swissprot:P52073; GLCE_ECOLI GLYCOLATE OXIDASE SUBUNIT GLCE; E=6e-23 pir:D82977; glycolate oxidase subunit GlcE PA5354 [imported] -; E=1e-22 COG: glcF_1; COG0277 FAD/FMN-containing dehydrogenases; E=6e-24 PFAM: PF01565; FAD binding domain; E=6.6e-19.
 
 
 0.995
RB6394
Probable 2-hydroxyacid dehydrogenase; PMID: 10984043 best DB hits: BLAST: gb:AAH00605.1; AAH00605 (BC000605) glyoxylate; E=1e-66 ref:XP_005487.2; glyoxylate reductasehydroxypyruvate reductase; E=1e-66 gb:AAF51963.1; (AE003602) CG1236 gene product [Drosophila; E=7e-61 COG: APE1831; COG1052 Lactate dehydrogenase and related dehydrogenases; E=2e-60 PAB0514; COG0111 Phosphoglycerate dehydrogenase and related; E=3e-44 YNL274c; COG1052 Lactate dehydrogenase and related dehydrogenases; E=3e-34 PFAM: PF00389; D-isomer specific 2-hydroxyacid; E=2.4e-06 PF02826; D-isomer specific 2-hydroxyacid; [...]
    
 0.904
RB2754
Conserved hypothetical protein-putative phosphoglycolate phosphatase; PMID: 9371463 PMID: 7603433 best DB hits: BLAST: pir:E69106; hypothetical protein MTH1793 - Methanobacterium; E=3e-05 pir:T44528; phosphoglycolate phosphatase (EC 3.1.3.18) [imported] -; E=3e-04 gb:AAG42459.1; AF308467_5 (AF308467) Gph [Klebsiella aerogenes]; E=3e-04 COG: MTH1793; COG0546 Predicted phosphatases; E=3e-06 PFAM: PF00702; haloacid dehalogenase-like hydrolas; E=1.1e-16.
    
 0.901
katA
Catalase; PMID: 9358059 best DB hits: BLAST: gb:AAB26985.1; (L48340) catalase [Methylobacterium extorquens]; E=0.0 swissprot:Q59714; CATA_PSEPU CATALASE ----- gb: AAB88219.1; E=1e-152 swissprot:P48062; CATA_BORPE CATALASE ----- pir: S60757; E=1e-152 COG: PA4236; COG0753 Catalase; E=1e-153 PFAM: PF01334; Bacterioferritin; E=0.24 PF00199; Catalase; E=1.7e-261.
     
  0.900
RB7618
Putative electron transport protein ykgF-putative 4Fe-4S containing oxidoreductase; PMID: 97426617 PMID: 9278503 best DB hits: BLAST: swissprot:P77536; YKGF_ECOLI HYPOTHETICAL 53.1 KD PROTEIN IN; E=5e-89 gb:AAG54641.1; AE005208_9 (AE005208) orf, hypothetical protein; E=9e-89 pir:T36429; probable iron-sulfur protein SCF43A.06 [similarity] -; E=1e-86 COG: ykgF; COG1139 Uncharacterized conserved protein containing a; E=5e-90 AF0506; COG0247 Fe-S oxidoreductases; E=2e-05 PFAM: PF00037; 4Fe-4S binding domain; E=0.43.
 
 
 0.897
RB12038
Best DB hits: BLAST: ddbj:BAB04429.1; (AP001509) BH0710~unknown conserved protein; E=8e-91 pir:T34927; probable oxidoreductase - Streptomyces coelicolor; E=5e-84 embl:CAB88965.1; (AL353864) putative oxidoreductase; E=3e-46 COG: BH0710; COG0673 Predicted dehydrogenases and related proteins; E=7e-92 PFAM: PF01408; Oxidoreductase family, NAD-bin; E=7e-36 PF02894; Oxidoreductase family, C-termi; E=6.8e-06.
  
    0.777
RB12043
Hypothetical protein.
       0.773
RB7616
Conserved hypothetical protein; PMID: 99120557 best DB hits: BLAST: pir:G71971; hypothetical protein jhp0125 - Helicobacter pylori; E=9e-04 pir:T36430; hypothetical protein SCF43A.07 - Streptomyces coelicolor; E=0.002 pir:A64537; hypothetical protein HP0137 - Helicobacter pylori; E=0.003 COG: jhp0125; COG1556 Uncharacterized ACR; E=8e-05 APE0258; COG1139 Uncharacterized conserved protein containing a; E=0.007 ykgG; COG1556 Uncharacterized ACR; E=0.009 PFAM: PF02589; Uncharacterized ACR, YkgG family COG; E=2.3e-07.
  
 
 0.716
lldP
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.519
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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