STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB12572Serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=1e-32 gb:AAF73695.1; (AE002226) serinethreonine-protein kinase; E=3e-32 embl:CAA10713.1; (AJ132604) hypothetical protein [Lactococcus; E=1e-31 COG: BS_yloP_1; COG0515 Serine/threonine protein kinases; E=1e-33 PFAM: PF00069; Protein kinase domain; E=2.1e-33 PF00515; TPR Domain; E=0.017. (812 aa)    
Predicted Functional Partners:
RB12571
GGDEF family protein; PMID: 10567266 best DB hits: BLAST: pir:E75266; GGDEF family protein - Deinococcus radiodurans (strain; E=2e-27 gb:AAA87378.1; (L42554) pleD gene product [Caulobacter; E=2e-25 gb:AAD28578.1; AF121341_2 (AF121341) putative response regulator; E=3e-25 COG: DR2498; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-28 TM1594; COG2199 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); E=7e-21 yddV_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=9e-21 PFAM: PF00897; Orbivirus inner capsid protein VP7; E=0.89 PF00498; FHA domain; E=1.3e-19 PF [...]
  
 
 0.812
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.802
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
  
   0.802
RB10367
Best DB hits: BLAST: pir:C70986; probable serinethreonine protein kinase (EC 2.7.1.-) -; E=1e-17 embl:CAB66178.1; (AL136500) probable serinethreonine protein; E=1e-15 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=6e-15 COG: Rv1746; COG0515 Serine/threonine protein kinases; E=1e-18 PFAM: PF00069; Protein kinase domain; E=3.8e-28.
  
     0.774
RB12576
Hypothetical protein.
       0.572
efp-2
Translation elongation factor EF-P; PMID: 1956781 best DB hits: BLAST: swissprot:P33028; YEIP_ECOLI 30.9 KDA PROTEIN IN FRUB-SPR; E=3e-32 gb:AAG57309.1; AE005449_7 (AE005449) putative elongation factor; E=4e-32 pir:D82229; translation elongation factor EF-P VC1209 [imported] -; E=6e-31 COG: yeiP; COG0231 Translation elongation factor P/translation initiation; E=3e-33 VC1209; COG0231 Translation elongation factor P/translation; E=6e-32 efp; COG0231 Translation elongation factor P/translation initiation; E=4e-19 PFAM: PF01132; Elongation factor P (EF-P); E=1.9e-57.
       0.572
RB1789
PMID: 10484179 best DB hits: BLAST: ddbj:BAB05496.1; (AP001513) BH1777~unknown conserved protein; E=1e-04 ddbj:BAA14001.1; (D89626) adenylate cyclase [Anabaena sp.]; E=0.001 pir:B70700; hypothetical protein Rv0020c - Mycobacterium; E=0.003 COG: BH1777_1; COG1716 FHA-domain-containing proteins; E=5e-05 PFAM: PF00498; FHA domain; E=4.6e-18.
  
 
   0.402
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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