STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB146Probable cation efflux system; PMID: 8203018 best DB hits: BLAST: pir:C70415; cation efflux system (czcB-like) - Aquifex aeolicus; E=2e-10 pir:B82357; conserved hypothetical protein VC0165 [imported] -; E=3e-10 ddbj:BAA34299.1; (AB015853) MexX [Pseudomonas aeruginosa]; E=5e-08 COG: aq_1331; COG0845 Membrane-fusion protein; E=2e-11 emrA; COG1566 Multidrug resistance efflux pump; E=0.003 PA3402; COG0845 Membrane-fusion protein; E=0.003 PFAM: PF00364; Biotin-requiring enzyme; E=0.0052 PF00529; HlyD family secretion protein; E=6.1e-07; Belongs to the membrane fusion protein (MFP) (TC 8.A.1 [...] (295 aa)    
Predicted Functional Partners:
RB149
Probable outer membrane channel protein; PMID: 9852029 best DB hits: BLAST: gb:AAD12177.1; (AF029405) outer membrane channel protein; E=0.001 gb:AAD30205.1; (AF094824) IbeB [Escherichia coli]; E=0.039 swissprot:Q51487; OPRM_PSEAE OUTER MEMBRANE PROTEIN OPRM PRECURSOR; E=0.049 COG: PA0427; COG1538 Outer membrane protein; E=0.005 PFAM: PF02321; Outer membrane efflux protein; E=0.0013.
 
  0.971
RB144
Probable membrane-fusion protein; Best DB hits: BLAST: pir:T31342; ragD protein - Bradyrhizobium japonicum ----- embl:; E=1e-05 pir:B83186; probable RND efflux membrane fusion protein precursor; E=2e-04 gb:AAK03081.1; (AE006139) unknown [Pasteurella multocida]; E=0.001 COG: PA3677; COG0845 Membrane-fusion protein; E=2e-05 PA2836; COG1566 Multidrug resistance efflux pump; E=0.001 VC0165; COG0845 Membrane-fusion protein; E=0.002 PFAM: PF00364; Biotin-requiring enzyme; E=0.021.
 
     0.937
mexA
Multidrug resistance protein MexA; PMID: 7968531 best DB hits: BLAST: gb:AAD12178.1; (AF029405) periplasmic linker protein [Pseudomonas; E=8e-20 swissprot:P37636; YHIU_ECOLI HYPOTHETICAL 41.2 KD LIPOPROTEIN IN; E=3e-19 gb:AAG58654.1; AE005576_13 (AE005576) putative membrane protein; E=4e-19 COG: yhiU; COG0845 Membrane-fusion protein; E=3e-20 PFAM: PF00364; Biotin-requiring enzyme; E=0.0015 PF00529; HlyD family secretion protein; E=3.1e-06; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.923
RB142
Hypothetical protein-transmembrane prediction; Best DB hits: PFAM: PF00364; Biotin-requiring enzyme; E=0.031 PF00529; HlyD family secretion protein; E=0.78.
 
     0.873
ibeB-2
Probable outer membrane lipoprotein IbeB; PMID: 99242786 best DB hits: BLAST: gb:AAD30205.1; (AF094824) IbeB [Escherichia coli]; E=3e-33 swissprot:P77211; IBEB_ECOLI PROBABLE OUTER MEMBRANE LIPOPROTEIN; E=4e-33 gb:AAG54905.1; AE005237_1 (AE005237) putative resistance protein; E=1e-32 COG: ylcB; COG1538 Outer membrane protein; E=4e-34 PFAM: PF02321; Outer membrane efflux protein; E=1.3e-09.
   
  0.848
secA
PMID: 2542029 best DB hits: BLAST: pir:F82760; preprotein translocase SecA subunit XF0806 [imported] -; E=3e-73 ddbj:BAB07325.1; (AP001519) preprotein translocase subunit; E=1e-72 swissprot:P28366; SECA_BACSU PREPROTEIN TRANSLOCASE SECA SUBUNIT; E=7e-69 COG: XF0806; COG0653 Preprotein translocase subunit SecA (ATPase, RNA; E=3e-74 PFAM: PF01043; SecA protein, amino terminal reg; E=1e-16 PF00271; Helicase conserved C-terminal do; E=0.12.
       0.773
RB188
Probable membrane-fusion protein; Best DB hits: BLAST: pir:T31342; ragD protein - Bradyrhizobium japonicum ----- embl:; E=2e-20 pir:A83330; probable RND efflux membrane fusion protein precursor; E=2e-12 pir:D83099; probable RND efflux membrane fusion protein precursor; E=2e-12 COG: PA2528; COG0845 Membrane-fusion protein; E=2e-13 PFAM: PF00364; Biotin-requiring enzyme; E=0.18 PF00529; HlyD family secretion protein; E=0.05; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.763
RB1677
Hypothetical protein; Best DB hits: PFAM: PF02321; Outer membrane efflux protein; E=5.9e-09.
  
  0.704
RB183
Conserved hypothetical protein-putative outer membrane protein; PMID: 12093901 best DB hits: BLAST: gb:AAD51069.1; AF175716_1 (AF175716) immunoreactive 52kD antigen; E=0.045 pir:S75812; hypothetical protein slr1270 - Synechocystis sp. (strain; E=0.17 PFAM: PF02321; Outer membrane efflux protein; E=0.18.
  
  0.697
aprF
Similar to AprF-putative outer membrane efflux protein or secreted alkaline phosphatase; PMID: 11222613 best DB hits: BLAST: gb:AAF87592.1; AF286062_5 (AF286062) AprF [Pseudomonas; E=0.29 gb:AAF01330.1; (AF188365) outer membrane protein [Pseudomonas; E=0.64 PFAM: PF02321; Outer membrane efflux protein; E=2.3e-05.
  
  0.697
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.