STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
papSPoly A polymerase; PMID: 10192388 best DB hits: BLAST: pir:E72028; poly A polymerase - Chlamydophila pneumoniae (strains; E=9e-41 pir:B81744; poly(A) polymerase family protein TC0077 [imported] -; E=3e-40 pir:A71481; probable poly A polymerase - Chlamydia trachomatis; E=5e-40 COG: CPn0845; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; E=9e-42 PFAM: PF01743; Poly A polymerase family; E=2.6e-50; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (427 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
    0.877
pnp-2
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.679
aroA-2
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
    0.647
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
  
 0.643
RB7663
Conserved hypothetical protein-containing P-loop; Best DB hits: BLAST: swissprot:O83845; Y875_TREPA HYPOTHETICAL PROTEIN TP0875 -----; E=1e-09 pir:H72229; conserved hypothetical protein - Thermotoga maritima; E=2e-08 ddbj:BAB04264.1; (AP001508) BH0545~unknown conserved protein; E=1e-05 COG: TP0875; COG0802 Predicted ATPase or kinase; E=1e-10 PFAM: PF02367; Uncharacterised P-loop hydrolase UPF; E=3.9e-22.
 
     0.609
ribD
PMID: 9068650 best DB hits: BLAST: pir:T50546; riboflavin bifunctional biosynthesis protein ribG; E=2e-56 swissprot:P50853; RIBD_ACTPL RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBD; E=2e-56 ddbj:BAB05273.1; (AP001512) riboflavin specific; E=9e-52 COG: ribD_1; COG0117 Pyrimidine deaminase; E=1e-28 BH1554_2; COG1985 Pyrimidine reductase, riboflavin biosynthesis; E=6e-21 CPn0871_1; COG0117 Pyrimidine deaminase; E=1e-20 PFAM: PF00383; Cytidine and deoxycytidylate de; E=1.5e-31 PF01872; RibD C-terminal domain; E=4e-33.
  
    0.579
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
 
 
 0.579
RB1994
Hypothetical protein.
       0.572
spoIIIE
Stage III sporulation protein E; PMID: 3129532 PMID: 2507870 PMID: 8160014 best DB hits: BLAST: swissprot:P21458; SP3E_BACSU STAGE III SPORULATION PROTEIN E; E=1e-108 pir:C69999; DNA translocase stage III sporulation homolog ytpT -; E=1e-106 swissprot:P45264; FTSK_HAEIN CELL DIVISION PROTEIN FTSK HOMOLOG; E=1e-105 COG: BS_spoIIIE; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related; E=1e-109 ftsK; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; E=6e-97 CT739; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related; E=6e-97 PFAM: PF01580; FtsK/SpoIIIE family; E=9.7e-66.
 
   
 0.562
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
  
 0.547
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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