STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3373PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21. (1998 aa)    
Predicted Functional Partners:
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
 
 
0.999
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 
0.999
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
0.999
RB11986
Histidine protein kinase homolog GacS; PMID: 10762268 best DB hits: BLAST: gb:AAF04854.1; AF197912_1 (AF197912) histidine protein kinase; E=3e-57 pir:E83212; probable sensorresponse regulator hybrid PA3462; E=4e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=8e-51 COG: PA3462; COG0642 Sensory transduction histidine kinases; E=3e-57 PFAM: PF00989; PAS domain; E=3.5e-07 PF00512; His Kinase A (phosphoacceptor; E=2.5e-21 PF02518; Histidine kinase-, DNA gyrase; E=6.8e-39.
 
 
0.999
RB13112
PMID: 7984107 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=1e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-57 pir:C82424; sensor histidine kinase LuxQ VCA0736 [imported] - Vibrio; E=8e-56 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=8e-57 PFAM: PF00785; PAC motif; E=0.34 PF00512; His Kinase A (phosphoacceptor) d; E=8.1e-23 PF02518; Histidine kinase-, DNA gyrase B-; E=3.6e-41.
 
 
0.999
RB13175
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46.
 
 
0.999
RB13181
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=8e-57 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=4e-49 embl:CAA37397.1; (X53315) arcB [Escherichia coli]; E=3e-48 COG: sll1353_2; COG0642 Sensory transduction histidine kinases; E=7e-43 PFAM: PF00785; PAC motif; E=0.1 PF00989; PAS domain; E=8.8e-05 PF00785; PAC motif; E=9.8e-08.
 
 
0.999
RB159
PMID: 11406410 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-63 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=8e-62 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-53 PFAM: PF00989; PAS domain; E=5.9e-05 PF00512; His Kinase A (phosphoacceptor); E=4.2e-24 PF02518; Histidine kinase-, DNA gyrase B; E=4.1e-43.
 
 
0.999
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
0.999
RB641
Sensory histidine protein kinase; Best DB hits: BLAST: pir:G82753; two-component system, sensor protein XF0853 [imported] -; E=2e-41 gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=8e-39 pir:A82300; sensory box sensor histidine kinaseresponse regulator; E=4e-34 COG: XF0853; COG0642 Sensory transduction histidine kinases; E=2e-42 sll0779_1; COG2202 PAS/PAC domain; E=1e-23 VCA0736_1; COG0642 Sensory transduction histidine kinases; E=1e-23 PFAM: PF00785; PAC motif; E=8.5e-08 PF00989; PAS domain; E=0.013 PF00785; PAC motif; E=0.1.
 
 
0.999
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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