STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3938Hypothetical protein; Best DB hits: PFAM: PF01522; Polysaccharide deacetylase; E=0.37. (195 aa)    
Predicted Functional Partners:
RB3940
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAC27019.1; (AF032114) unknown [Methylobacterium extorquens]; E=2e-16 pir:B75078; hypothetical protein PAB1694 - Pyrococcus abyssi (strain; E=5e-16 pir:F71066; hypothetical protein PH1228 - Pyrococcus horikoshii; E=2e-15 COG: PAB1694; COG1907 Predicted archaeal sugar kinases; E=5e-17.
 
     0.954
RB1696
Conserved hypothetical protein-putative dihydropteroate synthase; PMID: 8688087 best DB hits: BLAST: swissprot:Q57571; Y107_METJA HYPOTHETICAL PROTEIN MJ0107 -----; E=5e-21 gb:AAB89833.1; (AE001006) dihydropteroate synthase [Archaeoglobus; E=1e-20 pir:H69099; conserved hypothetical protein MTH1741 -; E=1e-16 COG: MJ0107; COG0294 Dihydropteroate synthase; E=5e-22.
 
     0.807
trpG
Anthranilate synthase component II; PMID: 2656657 PMID: 6283099 PMID: 2404959 best DB hits: BLAST: pir:B82835; anthranilate synthase component II XF0211 [imported] -; E=4e-40 swissprot:P06193; PABA_SALTY PARA-AMINOBENZOATE SYNTHASE GLUTAMINE; E=4e-39 pir:NNPS2P; anthranilate synthase (EC 4.1.3.27) component II; E=6e-39 COG: XF0211; COG0512 Anthranilate/para-aminobenzoate synthases component; E=3e-41 TM0141_1; COG0512 Anthranilate/para-aminobenzoate synthases; E=7e-37 DR1766; COG0512 Anthranilate/para-aminobenzoate synthases component; E=3e-36 PFAM: PF00117; Glutamine amidotransferase c [...]
       0.806
RB10246
Conserved hypothetical protein; PMID: 9651254 PMID: 10215859 PMID: 10848995 PMID: 11073907 best DB hits: BLAST: gb:AAG32953.1; (AF032114) unknown [Methylobacterium extorquens]; E=2e-21 pir:D69199; conserved hypothetical protein MTH743 - Methanobacterium; E=6e-18 swissprot:Q57680; Y227_METJA HYPOTHETICAL PROTEIN MJ0227 -----; E=2e-16 COG: MTH743; COG1767 Uncharacterized ACR; E=5e-19 PFAM: PF01874; CitG family; E=1.9e-07.
 
     0.801
RB5685
Conserved hypothetical protein; PMID: 9389475 best DB hits: BLAST: gb:AAB89060.1; (AE000954) conserved hypothetical protein; E=7e-11 gb:AAD23399.1; AF110772_1 (AF110772) unknown [Streptomyces; E=1e-10 pir:G69054; conserved hypothetical protein MTH141 - Methanobacterium; E=1e-10 COG: AF2196; COG1891 Uncharacterized ArCR; E=7e-12.
 
     0.801
RB10299
Conserved hypothetical protein; PMID: 9651254 PMID: 10215859 PMID: 10848995 PMID: 11073907 best DB hits: BLAST: gb:AAC27021.1; (AF032114) unknown [Methylobacterium extorquens]; E=0.029 embl:CAB92281.1; (AL356595) hypothetical protein [Streptomyces; E=0.43 pir:C83094; D-alanine--D-alanine ligase PA4410 [imported] -; E=0.62 PFAM: PF00826; Ribosomal L10; E=0.66.
 
     0.795
fwdA
Putative formylmethanofuran dehydrogenase subunit A; PMID: 9651254 PMID: 10215859 PMID: 10848995 PMID: 11073907 best DB hits: BLAST: gb:AAG32950.1; (AF032114) putative formylmethanofuran; E=6e-98 pir:S57456; formylmethanofuran dehydrogenase (EC 1.2.99.5); E=8e-72 pir:G69074; formylmethanofuran dehydrogenase (EC 1.2.99.5); E=3e-71 COG: MTH1557; COG1229 Formylmethanofuran dehydrogenase subunit A; E=3e-72 PFAM: PF02612; N-acetylglucosamine-6-phosphat; E=0.0077.
 
     0.795
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
     0.794
ffsA
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase ffsA; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
     0.794
fwdC-2
Tungsten formylmethanofuran dehydrogenase, subunit C (fwdC); PMID: 8575452 best DB hits: BLAST: gb:AAB89324.1; (AE000970) tungsten formylmethanofuran; E=2e-17 pir:T45154; probable formylmethanofuran dehydrogenase (EC 1.2.99.5); E=3e-17 swissprot:Q59579; FWDC_METTM TUNGSTEN-CONTAINING; E=2e-14 COG: AF1931; COG2218 Formylmethanofuran dehydrogenase subunit C; E=2e-18 TM0394; COG0070 Glutamate synthetase domain 3; E=2e-06 MJ0658; COG2218 Formylmethanofuran dehydrogenase subunit C; E=0.001 PFAM: PF01493; Domain of unknown function DUF14; E=1.3e-06.
 
     0.794
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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