STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4728Putative serine/threonine kinase; PMID: 11410353 PMID: 10627033 PMID: 10496921 PMID: 9001395 best DB hits: BLAST: pir:G71532; probable threoninetyrosine-specific protein kinase (EC; E=1e-25 gb:AAF73573.1; (AE002326) serinethreonine protein kinase; E=5e-22 pir:T36501; probable serinethreonine protein kinase - Streptomyces; E=3e-20 COG: CT301_1; COG0515 Serine/threonine protein kinases; E=1e-26 PFAM: PF02473; Oxygen-independent Coproporphy; E=0.8 PF00069; Protein kinase domain; E=5.9e-29. (344 aa)    
Predicted Functional Partners:
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.802
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
  
   0.801
RB10333
Protein kinase homolog; Best DB hits: BLAST: pir:T42076; protein kinase homolog - Streptomyces coelicolor -----; E=5e-18 pir:T42077; protein kinase homolog - Streptomyces coelicolor -----; E=1e-16 pir:T35491; probable serinethreonine-specific protein kinase pkaF -; E=1e-16 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=3e-15 PFAM: PF00069; Protein kinase domain; E=3.2e-06.
  
     0.775
RB12694
Probable serine/threonine kinase; PMID: 7768349 best DB hits: BLAST: pir:T42076; protein kinase homolog - Streptomyces coelicolor -----; E=2e-12 gb:AAG48248.1; AF282407_1 (AF282407) p70 ribosomal protein S6; E=2e-12 gb:AAF22219.1; AF141378_1 (AF141378) protein kinase PK4 [Zea mays]; E=2e-12 COG: BS_yloP_1; COG0515 Serine/threonine protein kinases; E=2e-12 PFAM: PF01636; Aminoglycoside phosphotransferas; E=0.093 PF00069; Protein kinase domain; E=6.3e-17 PF00285; Citrate synthase; E=0.22.
  
     0.775
RB3893
Serine/threonine protein kinase; PMID: 11337471 best DB hits: BLAST: pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=1e-22 gb:AAK05985.1; AE006418_5 (AE006418) serinethreonine protein; E=1e-22 embl:CAA10713.1; (AJ132604) hypothetical protein [Lactococcus; E=2e-22 COG: BH2504_1; COG0515 Serine/threonine protein kinases; E=1e-21 PFAM: PF00069; Protein kinase domain; E=3.4e-39.
  
     0.775
ppkA-3
Serine/threonine protein kinase PpkA; PMID: 7883195 best DB hits: BLAST: gb:AAD03499.2; (AF035395) serinethreonine protein kinase PpkA; E=6e-16 pir:D83637; serinethreonine protein kinase PpkA PA0074 [imported] -; E=1e-15 pir:T36502; serinethreonine protein kinase - Streptomyces; E=2e-11 COG: PA0074; COG0515 Serine/threonine protein kinases; E=1e-16 PFAM: PF00069; Protein kinase domain; E=1e-08.
  
     0.775
RB10367
Best DB hits: BLAST: pir:C70986; probable serinethreonine protein kinase (EC 2.7.1.-) -; E=1e-17 embl:CAB66178.1; (AL136500) probable serinethreonine protein; E=1e-15 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=6e-15 COG: Rv1746; COG0515 Serine/threonine protein kinases; E=1e-18 PFAM: PF00069; Protein kinase domain; E=3.8e-28.
  
     0.774
RB419
Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:Q11053; PKNH_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=5e-14 pir:T42076; protein kinase homolog - Streptomyces coelicolor -----; E=2e-13 pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=4e-13 COG: Rv1266c; COG0515 Serine/threonine protein kinases; E=5e-15 PFAM: PF00069; Protein kinase domain; E=3.3e-32.
  
     0.774
RB4729
Hypothetical protein-signal peptide prediction.
       0.773
RB4730
Hypothetical protein.
  
    0.574
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.