STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB5028PMID: 8969512 best DB hits: BLAST: pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=6e-44 swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=1e-37 swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=3e-37 COG: BS_yloP_1; COG0515 Serine/threonine protein kinases; E=6e-45 PFAM: PF00069; Protein kinase domain; E=1.5e-45 PF00004; ATPase family associated with vari; E=0.14 PF00005; ABC transporter; E=0.082. (1813 aa)    
Predicted Functional Partners:
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
 
 
 0.814
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
 
 
 0.809
RB505
Similar to myosin heavy chain; PMID: 11403381 best DB hits: BLAST: embl:CAC28360.1; (AJ306290) myosin heavy chain [Toxocara canis]; E=0.054 gb:AAD29950.1; (AF111784) myosin heavy chain IIa [Homo sapiens]; E=0.19.
 
    0.686
RB10149
Best DB hits: BLAST: swissprot:P33450; FAT_DROME CADHERIN-RELATED TUMOR SUPPRESSOR; E=0.68 pir:IJFFTM; cadherin-related tumor suppressor precursor - fruit fly; E=0.68 gb:AAF51036.1; (AE003577) ft gene product [Drosophila melanogaster]; E=0.68 PFAM: PF00028; Cadherin domain; E=0.014 PF00801; PKD domain; E=0.0048 PF02101; Ocular albinism type 1 protei; E=0.26.
  
     0.609
RB502
Hypothetical protein-signal peptide prediction; PMID: 11474104.
  
     0.535
RB1661
Hypothetical protein; PMID: 96163873 best DB hits: BLAST: embl:CAA60685.1; (X87241) homologue of Drosophila Fat protein [Homo; E=3e-18 embl:CAB65271.1; (AJ250768) mouse fat 1 cadherin [Mus musculus]; E=1e-17 PFAM: PF00054; Laminin G domain; E=0.3 PF00354; Pentaxin family; E=3.9e-10 PF00059; Lectin C-type domain; E=0.00071.
  
    0.498
RB5029
Best DB hits: BLAST: embl:CAC11769.1; (AL445064) conserved hypothetical protein; E=9e-08 pir:F70426; conserved hypothetical protein aq_1457 - Aquifex; E=4e-07 embl:CAB88946.1; (AL353863) putative methyltransferase; E=7e-07 COG: Ta0630; COG0500 SAM-dependent methyltransferases; E=9e-09 VC0083; COG2226 Methylase involved in ubiquinone/menaquinone; E=2e-05 aq_262; COG0500 SAM-dependent methyltransferases; E=1e-04.
       0.486
RB5031
Hypothetical protein-transmembrane region and signal peptide prediction; Best DB hits: BLAST: pir:T34929; hypothetical protein SC3F9.07 SC3F9.07 - Streptomyces; E=0.005.
       0.486
RB9317
Probable threonine/tyrosine-specific protein kinase; PMID: 99000809 PMID: 97000351 best DB hits: BLAST: pir:G71532; probable threoninetyrosine-specific protein kinase (EC; E=4e-30 gb:AAF73573.1; (AE002326) serinethreonine protein kinase; E=3e-27 embl:CAB45034.1; (AL078635) putative WD-repeat containing protein; E=3e-26 COG: CT301_1; COG0515 Serine/threonine protein kinases; E=3e-31 sll0163; COG2319 WD40 repeat protein; E=1e-19 Rv1266c; COG0515 Serine/threonine protein kinases; E=1e-19 PFAM: PF00069; Protein kinase domain; E=1.1e-26 PF00400; WD domain, G-beta repeat; E=7.5e-06.
 
  
0.455
ptfA
Probable fructose specific permease-possibly phosphotransferase system component; PMID: 20175229 best DB hits: BLAST: ddbj:BAB03332.1; (AB035450) fructose specific permease; E=3e-07 pir:H69626; PTS fructose-specific enzyme IIBC component fruA -; E=5e-07 pir:B81941; probable regulatory protein NMA0946 [imported] -; E=9e-07 COG: BS_fruA_1; COG1762 Phosphotransferase system; E=5e-08 TP0755; COG1762 Phosphotransferase system mannitol/fructose-specific; E=6e-07 VC1826_1; COG1762 Phosphotransferase system; E=8e-07.
 
   0.444
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.