STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (507 aa)    
Predicted Functional Partners:
glgC-2
ADP-glucose pyrophosphorylase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 0.997
glgB
1,4-alpha-glucan branching enzyme (glycogen branching enzyme); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.997
glgC
Glucose-1-phosphate adenylyltransferase; PMID: 1325205 best DB hits: BLAST: swissprot:P30521; GLGC_ANASP GLUCOSE-1-PHOSPHATE; E=1e-102 prf:1905422A; ADP-glucose pyrophosphorylase [Synechocystis sp.]; E=1e-101 swissprot:P52415; GLGC_SYNY3 GLUCOSE-1-PHOSPHATE; E=1e-101 COG: slr1176; COG0448 ADP-glucose pyrophosphorylase; E=1e-102 MTH1759; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylases; E=3e-27 BH1086; COG0448 ADP-glucose pyrophosphorylase; E=3e-13 PFAM: PF00483; Nucleotidyl transferase; E=8.7e-62 PF00132; Bacterial transferase hexapep; E=0.029; Belongs to the bacterial/plant glu [...]
 
 0.996
glgB-2
1,4-alpha-glucan branching enzyme; PMID: 8068720 PMID: 3013861 best DB hits: BLAST: swissprot:P52980; GLGB_STRAU 1,4-ALPHA-GLUCAN BRANCHING ENZYME; E=2e-46 swissprot:P30537; GLGB_BACCL 1,4-ALPHA-GLUCAN BRANCHING ENZYME; E=7e-45 pir:D82511; 1,4-alpha-glucan branching enzyme VCA0016 [imported] -; E=1e-44 COG: VCA0016; COG0296 1,4-alpha-glucan branching enzyme; E=1e-45 BS_amyX; COG1523 Pullulanase and related glycosidases; E=2e-21 YEL011w; COG0296 1,4-alpha-glucan branching enzyme; E=3e-20 PFAM: PF02922; Isoamylase N-terminal domain; E=2.3e-15 PF01208; Uroporphyrinogen decarboxylas; E=0.2 [...]
 
 0.991
glgP
Phosphorylase 2; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 0.972
malQ
4-alpha-glucanotransferase; PMID: 10677288 best DB hits: BLAST: swissprot:O87172; MALQ_THEAQ 4-ALPHA-GLUCANOTRANSFERASE; E=1e-119 swissprot:P72785; MALQ_SYNY3 4-ALPHA-GLUCANOTRANSFERASE; E=1e-118 swissprot:P29851; MALQ_STRPN 4-ALPHA-GLUCANOTRANSFERASE; E=1e-114 COG: sll1676; COG1640 4-alpha-glucanotransferase; E=1e-119 PFAM: PF02446; 4-alpha-glucanotransferase; E=3.9e-185.
 
 
 0.962
RB2160
Alpha-amylase; PMID: 2453362 best DB hits: BLAST: swissprot:P09961; AMY1_DICTH ALPHA-AMYLASE 1 (1,4-ALPHA-D-GLUCAN; E=1e-120 ddbj:BAA22063.1; (D88253) 4-alpha-glucanotransferase; E=1e-114 ddbj:BAA22062.1; (D87907) 4-alpha-glucanotransferase [Pyrococcus; E=1e-112 COG: PAB0118; COG1449 Alpha-amylase/alpha-mannosidase; E=1e-111 Rv3031; COG1543 Uncharacterized ACR; E=1e-04.
 
 
  0.930
glgX-2
Glycogen operon protein glgX-2; PMID: 97061201 PMID: 10333591 PMID: 10669803 best DB hits: BLAST: pir:S77094; glycogen operon protein (EC 3.2.1.-) glgX-2 -; E=1e-149 pir:S74546; glycogen operon protein (EC 3.2.1.-) glgX-1 -; E=1e-139 embl:CAB92884.1; (AL356932) putative glycogen debranching enzyme; E=1e-136 COG: slr1857; COG1523 Pullulanase and related glycosidases; E=1e-151 DR0464; COG0296 1,4-alpha-glucan branching enzyme; E=3e-17 DR0405; COG1523 Pullulanase and related glycosidases; E=3e-12 PFAM: PF02922; Isoamylase N-terminal domain; E=1.3e-22 PF00128; Alpha amylase, catalytic doma [...]
 
  
 0.878
RB5200
Alpha-amylase; PMID: 1747104 best DB hits: BLAST: ddbj:BAA11010.1; (D64130) alpha-amylase [Sulfolobus solfataricus]; E=4e-93 pir:JC5135; alpha-amylase (EC 3.2.1.1) - Sulfolobus solfataricus; E=4e-93 pir:S73087; alpha-amylase (EC 3.2.1.1) precursor - Sulfolobus; E=1e-89 COG: Rv1562c; COG0296 1,4-alpha-glucan branching enzyme; E=6e-72 BS_amyX; COG1523 Pullulanase and related glycosidases; E=1e-14 YEL011w; COG0296 1,4-alpha-glucan branching enzyme; E=1e-12 PFAM: PF00128; Alpha amylase, catalytic domain; E=2.4e-17; Belongs to the glycosyl hydrolase 13 family.
  
  
 0.872
glgX
Glycogen operon protein glgX-2; PMID: 8905231 PMID: 92082464 PMID: 93356744 best DB hits: BLAST: pir:S77094; glycogen operon protein (EC 3.2.1.-) glgX-2 -; E=1e-125 pir:S74546; glycogen operon protein (EC 3.2.1.-) glgX-1 -; E=1e-124 pir:S73088; glycogen operon protein glgX (EC 3.2.1.-) - Sulfolobus; E=1e-113 COG: slr1857; COG1523 Pullulanase and related glycosidases; E=1e-126 DR0464; COG0296 1,4-alpha-glucan branching enzyme; E=7e-17 DR0405; COG1523 Pullulanase and related glycosidases; E=8e-15 PFAM: PF02922; Isoamylase N-terminal domain; E=6.7e-23 PF00128; Alpha amylase, catalytic dom [...]
 
  
 0.822
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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