STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB7190Conserved hypothetical protein-putative regulatory protein; PMID: 10360571 best DB hits: BLAST: pir:C72374; hypothetical protein TM0467 - Thermotoga maritima; E=3e-16 embl:CAB56681.1; (AL121596) hypothetical protein SCF51A.29c; E=2e-14 embl:CAC01561.1; (AL391039) conserved hypothetical protein; E=4e-14 COG: TM0467; COG2208 Serine phosphatase RsbU, regulator of sigma subunit; E=3e-17 Rv1827; COG1716 FHA-domain-containing proteins; E=1e-09 slr1860_2; COG2208 Serine phosphatase RsbU, regulator of sigma; E=4e-09 PFAM: PF00498; FHA domain; E=1.4e-20 PF01590; GAF domain; E=3.5e-17. (634 aa)    
Predicted Functional Partners:
RB1764
Conserved hypothetical protein-putative transcription regulator; Best DB hits: BLAST: gb:AAG59798.1; AF292097_4 (AF292097) SenB [Leptospira interrogans]; E=4e-06 gb:AAC23717.1; (AF031161) transcriptional activator [Pseudomonas; E=0.004 pir:C82379; response regulator VCA1086 [imported] - Vibrio cholerae; E=0.005 COG: VCA1086_2; COG2208 Serine phosphatase RsbU, regulator of sigma; E=5e-04 TP0995; COG0664 cAMP-binding domains - Catabolite gene activator and; E=0.002 PFAM: PF00072; Response regulator receiver doma; E=0.29 PF02518; Histidine kinase-, DNA gyrase B-; E=0.65.
 
 
 0.970
RB12506
Probable anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PMID: 9266669 best DB hits: BLAST: ddbj:BAB05255.1; (AP001512) anti-sigma F factor antagonist (stage; E=0.003 pir:S75220; hypothetical protein slr1912 - Synechocystis sp. (strain; E=0.024 COG: BH1536; COG1366 Anti-anti-sigma regulatory factor (antagonist of; E=3e-04 PFAM: PF01740; STAS domain; E=4.9e-06.
  
 
 0.938
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
  
 
 0.930
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
  
 0.924
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
 
  
 0.909
RB159
PMID: 11406410 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-63 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=8e-62 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-53 PFAM: PF00989; PAS domain; E=5.9e-05 PF00512; His Kinase A (phosphoacceptor); E=4.2e-24 PF02518; Histidine kinase-, DNA gyrase B; E=4.1e-43.
 
  
 0.908
fliN
PMID: 2651416 best DB hits: BLAST: swissprot:P35539; FLIN_ERWCA FLAGELLAR MOTOR SWITCH PROTEIN FLIN; E=2e-04 swissprot:P15070; FLIN_ECOLI FLAGELLAR MOTOR SWITCH PROTEIN FLIN; E=5e-04 swissprot:P26419; FLIN_SALTY FLAGELLAR MOTOR SWITCH PROTEIN FLIN; E=5e-04 COG: TM0680a; COG1886 Flagellar motor switch/type III secretory pathway; E=2e-06 PFAM: PF01052; Surface presentation of antigens (SP; E=2.3e-07.
  
 
 0.849
fliN-2
Flagellar motor switch protein fliN (fragment); PMID: 2656645 PMID: 2651416 best DB hits: BLAST: swissprot:P35539; FLIN_ERWCA FLAGELLAR MOTOR SWITCH PROTEIN FLIN; E=5e-16 swissprot:P24073; FLIY_BACSU FLAGELLAR MOTOR SWITCH PROTEIN FLIY; E=8e-16 swissprot:P26419; FLIN_SALTY FLAGELLAR MOTOR SWITCH PROTEIN FLIN; E=2e-15 COG: BS_fliY_2; COG1886 Flagellar motor switch/type III secretory pathway; E=6e-17 PFAM: PF01052; Surface presentation of antigens (SP; E=2.5e-25.
  
 
 0.849
RB12501
Hypothetical protein; Best DB hits: PFAM: PF02361; Cobalt transport protein; E=0.17.
  
 
 0.847
RB7495
Conserved hypothetical protein-containing TPR-domains; PMID: 11932238 best DB hits: BLAST: gb:AAD38597.1; AF145622_1 (AF145622) BcDNA.GH04245 [Drosophila; E=6e-08 gb:AAG22339.1; (AE003787) Ogt gene product [alt 3] [Drosophila; E=6e-08 swissprot:P56558; OGT1_RAT UDP-N-ACETYLGLUCOSAMINE--PEPTIDE; E=9e-08 COG: MTH72; COG0457 TPR-repeat-containing proteins; E=9e-07 PFAM: PF00515; TPR Domain; E=0.017 PF00671; Iron/Ascorbate oxidoreductase; E=0.67 PF00515; TPR Domain; E=0.21.
  
 
 0.829
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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