STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degP-4Periplasmic serine proteinase DO; PMID: 99287316 best DB hits: BLAST: pir:F72359; periplasmic serine proteinase Do (EC 3.4.21.-) -; E=6e-26 pir:B81728; serine proteinase, HtrADegQ/DegS family TC0210; E=6e-25 swissprot:P18584; DEGP_CHLTR PROBABLE SERINE PROTEASE DO-LIKE; E=7e-25 COG: TM0571; COG0265 Trypsin-like serine proteases, typically; E=5e-27 CT823; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=6e-26 Cj1228c; COG0265 Trypsin-like serine proteases, typically; E=8e-26 PFAM: PF00089; Trypsin; E=1.7e-09 PF00595; PDZ domain (Also known as DHR or GLG; E=0.0017. (635 aa)    
Predicted Functional Partners:
degP-5
PMID: 20150255 best DB hits: BLAST: pir:B81728; serine proteinase, HtrADegQ/DegS family TC0210; E=1e-16 swissprot:P18584; DEGP_CHLTR PROBABLE SERINE PROTEASE DO-LIKE; E=2e-16 swissprot:Q9Z6T0; DEGP_CHLPN PROBABLE SERINE PROTEASE DO-LIKE; E=1e-15 COG: CT823; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=2e-17 CPn0979; COG0265 Trypsin-like serine proteases, typically; E=1e-16 RP124; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=3e-08 PFAM: PF00595; PDZ domain (Also known as DHR or GL; E=1.4e-09.
 
    
0.864
degP-6
HtrA [similar to serine proteases, trypsin family]; PMID: 21145866 best DB hits: BLAST: gb:AAK02818.1; (AE006110) HtrA [Pasteurella multocida]; E=4e-23 swissprot:P45129; HTOA_HAEIN PROBABLE PERIPLASMIC SERINE PROTEASE; E=1e-21 gb:AAC38202.1; (AF018151) HtrA [Haemophilus influenzae]; E=2e-21 COG: HI1259; COG0265 Trypsin-like serine proteases, typically; E=1e-22 htrA; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=2e-17 NMB0532; COG0265 Trypsin-like serine proteases, typically; E=2e-17 PFAM: PF00595; PDZ domain (Also known as DHR or GLG; E=8.4e-09.
 
    
0.864
RB7364
Hypothetical protein-signal peptide prediction.
       0.628
RB7363
Hypothetical protein.
       0.565
RB7374
Conserved hypothetical protein; PMID: 12101309 best DB hits: BLAST: pir:S76547; hypothetical protein - Synechocystis sp. (strain PCC; E=0.020 pir:C71559; probable outer membrane leader peptide CT073 - Chlamydia; E=0.27 pir:A81713; conserved hypothetical protein TC0345 [imported] -; E=0.41.
       0.509
RB5932
Polyprenyl synthetase; PMID: 8182085 PMID: 2198286 best DB hits: BLAST: pir:E71101; probable geranylgeranyl pyrophosphate synthetase -; E=9e-17 gb:AAD47627.1; (AF153713) octylprenyl diphosphate synthase-like; E=1e-16 swissprot:Q53479; IDSA_METTM BIFUNCTIONAL SHORT CHAIN ISOPRENYL; E=2e-15 COG: PH1072; COG0142 Geranylgeranyl pyrophosphate synthase; E=9e-18 AF0204; COG1852 Uncharacterized ArCR; E=3e-13 NMB0261; COG0142 Geranylgeranyl pyrophosphate synthase; E=4e-13 PFAM: PF01976; Protein of unknown function D; E=6e-24 PF00348; Polyprenyl synthetase; E=3.4e-09.
 
     0.496
ogt-3
Probable O-linked GlcNAc transferase; PMID: 9083067 best DB hits: COG: BH1262; COG0457 TPR-repeat-containing proteins; E=3e-05 PFAM: PF00533; BRCA1 C Terminus (BRCT) domain; E=7.9e-06 PF00515; TPR Domain; E=0.012.
  
     0.477
pnp-2
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
    0.475
RB10641
Probable beta-subunit of geranylgeranyltransferase or farnesyltransferase; Best DB hits: BLAST: ddbj:BAB10039.1; (AB007727) Rab geranylgeranyltransferase, beta; E=5e-05 swissprot:P41992; PFTB_CAEEL PROBABLE PROTEIN FARNESYLTRANSFERASE; E=7e-05 swissprot:Q04903; PFTB_PEA PROTEIN FARNESYLTRANSFERASE BETA; E=0.005 PFAM: PF00432; Prenyltransferase and squalene ox; E=1.4e-08.
  
     0.453
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
   0.448
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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