STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trkHPMID: 7896723 best DB hits: BLAST: gb:AAB90400.1; (AE001046) TRK potassium uptake system protein; E=8e-61 pir:G82037; potassium uptake protein TrkH VC2756 [imported] - Vibrio; E=4e-49 swissprot:P44843; TRKH_HAEIN TRK SYSTEM POTASSIUM UPTAKE PROTEIN; E=1e-46 COG: AF0839; COG0168 Trk-type K+ transport systems, membrane components; E=8e-62 NMB0661_2; COG0168 Trk-type K+ transport systems, membrane; E=1e-36 PA3210; COG0168 Trk-type K+ transport systems, membrane components; E=1e-36 PFAM: PF02386; Sodium transport protein; E=1.1e-54. (605 aa)    
Predicted Functional Partners:
trkA
TRK potassium uptake system protein (trkA-2); PMID: 8268235 PMID: 8412700 best DB hits: BLAST: gb:AAB90401.1; (AE001046) TRK potassium uptake system protein; E=4e-41 pir:T45222; heat shock protein trkA [imported] - Methanosarcina; E=2e-38 pir:E83643; potassium uptake protein TrkA PA0016 [imported] -; E=3e-38 COG: AF0838; COG0569 K+ transport systems, NAD-binding component; E=4e-42 PFAM: PF02254; KTN NAD-binding domain; E=1.1e-15 PF02080; Potassium channel; E=2.9e-12 PF02254; KTN NAD-binding domain; E=3.1e-08.
 
 
 0.975
RB12424
Potassium channel; PMID: 1550672 best DB hits: BLAST: pir:A82682; ion transporter XF1426 [imported] - Xylella fastidiosa; E=1e-48 pir:E75470; probable ion transporter - Deinococcus radiodurans; E=5e-42 pir:B83459; probable potassium channel PA1496 [imported] -; E=1e-36 COG: XF1426; COG1226 Kef-type K+ transport systems, predicted NAD-binding; E=1e-49 APE0955; COG1226 Kef-type K+ transport systems, predicted; E=7e-09 BH3340; COG1226 Kef-type K+ transport systems, predicted NAD-binding; E=4e-05 PFAM: PF01145; SPFH domain / Band 7 family; E=0.42 PF00520; Ion transport protein; E=5.1e-21.
  
 
 0.892
RB8290
Conserved hypothetical protein-putative potassium channel; PMID: 8170937 best DB hits: BLAST: pir:S76018; hypothetical protein - Synechocystis sp. (strain PCC; E=2e-61 swissprot:Q58752; YD57_METJA PUTATIVE POTASSIUM CHANNEL PROTEIN; E=1e-36 swissprot:Q57604; Y13B_METJA PUTATIVE POTASSIUM CHANNEL PROTEIN; E=2e-34 COG: sll0536; COG1226 Kef-type K+ transport systems, predicted; E=1e-62 MJ1357; COG1226 Kef-type K+ transport systems, predicted NAD-binding; E=1e-37 MJ0138.1; COG1226 Kef-type K+ transport systems, predicted; E=2e-35 PFAM: PF00520; Ion transport protein; E=0.45 PF02254; KTN NA [...]
  
 
 0.892
RB7673
Conserved hypothetical protein-putative periplasmatic serine protease; Best DB hits: BLAST: ddbj:BAB05075.1; (AP001511) BH1356~unknown conserved protein; E=1e-25 swissprot:P54465; YQEZ_BACSU HYPOTHETICAL 46.5 KD PROTEIN IN; E=6e-22 gb:AAB89465.1; (AE000979) nodulation protein NfeD (nfeD); E=8e-04 COG: BH1356_1; COG1030 Periplasmic serine proteases (ClpP class); E=1e-17 BH1356_2; COG1585 Membrane protein implicated in regulation of; E=1e-07 AF1781_1; COG1030 Periplasmic serine proteases (ClpP class); E=7e-05 PFAM: PF01957; Protein of unknown function DUF107; E=0.53.
 
     0.804
pcxB
PMID: 8407791 best DB hits: BLAST: pir:E83626; protocatechuate 3,4-dioxygenase, beta subunit PA0153; E=1e-14 pir:T35018; protocatechuate 3,4-dioxygenase beta chain -; E=1e-14 gb:AAF65837.1; AF253466_3 (AF253466) protocatechuate; E=3e-14 PFAM: PF00652; QXW lectin repeat; E=0.28 PF00775; Dioxygenase; E=3.6e-18.
       0.592
RB7681
Hypothetical protein.
       0.592
mscL
Probable large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.458
RB7682
Hypothetical protein.
  
    0.456
uroD
Uroporphyrinogen III synthase, uroporhyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.454
ptfA
Probable fructose specific permease-possibly phosphotransferase system component; PMID: 20175229 best DB hits: BLAST: ddbj:BAB03332.1; (AB035450) fructose specific permease; E=3e-07 pir:H69626; PTS fructose-specific enzyme IIBC component fruA -; E=5e-07 pir:B81941; probable regulatory protein NMA0946 [imported] -; E=9e-07 COG: BS_fruA_1; COG1762 Phosphotransferase system; E=5e-08 TP0755; COG1762 Phosphotransferase system mannitol/fructose-specific; E=6e-07 VC1826_1; COG1762 Phosphotransferase system; E=8e-07.
   
 
 0.434
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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