STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pknPutative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=3e-29 pir:T35491; probable serinethreonine-specific protein kinase pkaF -; E=1e-25 gb:AAF79944.1; AF233851_2 (AF233851) eukaryotic-type; E=1e-25 COG: Rv0015c; COG0515 Serine/threonine protein kinases; E=3e-26 PFAM: PF00069; Protein kinase domain; E=7.1e-37. (937 aa)    
Predicted Functional Partners:
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
  
   0.801
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.800
RB10367
Best DB hits: BLAST: pir:C70986; probable serinethreonine protein kinase (EC 2.7.1.-) -; E=1e-17 embl:CAB66178.1; (AL136500) probable serinethreonine protein; E=1e-15 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=6e-15 COG: Rv1746; COG0515 Serine/threonine protein kinases; E=1e-18 PFAM: PF00069; Protein kinase domain; E=3.8e-28.
  
     0.775
RB5876
Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:P54737; PKN5_MYXXA SERINETHREONINE-PROTEIN KINASE PKN5; E=3e-09 gb:AAF87930.1; AF163841_9 (AF163841) putative serinethreonine; E=4e-09 swissprot:P54738; PKN6_MYXXA SERINETHREONINE-PROTEIN KINASE PKN6; E=1e-07 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=1e-07 PFAM: PF00069; Protein kinase domain; E=3.8e-08 PF01130; CD36 family; E=0.61.
  
     0.726
nccH
PMID: 7961470 best DB hits: BLAST: swissprot:Q44583; NCCH_ALCXX RNA POLYMERASE SIGMA FACTOR NCCH; E=6e-07 pir:H82073; RNA polymerase sigma-E factor VC2467 [imported] - Vibrio; E=3e-06 embl:CAB55345.1; (AJ010584) ECF sigma factor [Streptomyces; E=2e-05 COG: VC2467; COG1595 DNA-directed RNA polymerase specialized sigma; E=3e-07 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=9.7e-11.
   
   0.696
RB6417
Conserved hypothetical protein-putative FHA domain; PMID: 9634230 PMID: 7482699 best DB hits: BLAST: pir:B70700; hypothetical protein Rv0020c - Mycobacterium; E=8e-06 pir:T10015; hypothetical protein MLB1770.15c - Mycobacterium leprae; E=4e-05 ddbj:BAB20624.1; (AB052847) adenylate cyclase; E=0.001 COG: Rv0020c_2; COG1716 FHA-domain-containing proteins; E=4e-06 PFAM: PF00498; FHA domain; E=8.9e-17.
  
 
 
 0.520
RB1789
PMID: 10484179 best DB hits: BLAST: ddbj:BAB05496.1; (AP001513) BH1777~unknown conserved protein; E=1e-04 ddbj:BAA14001.1; (D89626) adenylate cyclase [Anabaena sp.]; E=0.001 pir:B70700; hypothetical protein Rv0020c - Mycobacterium; E=0.003 COG: BH1777_1; COG1716 FHA-domain-containing proteins; E=5e-05 PFAM: PF00498; FHA domain; E=4.6e-18.
  
 
 
 0.463
RB7789
Similar to tolB protein [precursor]; PMID: 8921895 best DB hits: BLAST: swissprot:P44677; TOLB_HAEIN TOLB PROTEIN PRECURSOR ----- pir:; E=0.67 pir:JC5213; tolB protein - Haemophilus influenzae -----gb:; E=0.72.
       0.425
RB7790
Hypothetical protein.
       0.425
RB7791
Hypothetical protein-transmembrane prediction; PMID: 12024217.
       0.425
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.