STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmBConserved hypothetical protein-putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (271 aa)    
Predicted Functional Partners:
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.803
RB4721
Best DB hits: BLAST: pir:S77109; hypothetical protein slr1870 - Synechocystis sp. (strain; E=1e-63 pir:D81437; hypothetical protein Cj0189c [imported] - Campylobacter; E=2e-24 pir:C71266; conserved hypothetical protein TP0894 - syphilis; E=8e-20 COG: slr1870; COG1432 Uncharacterized ACR; E=1e-64.
  
  
 0.676
sun
Sun/nucleolar protein family protein-putative tRNA and rRNA cytosine-C5-methylase; Best DB hits: BLAST: pir:A82193; Sunnucleolar protein family protein VC1502 [imported] -; E=3e-23 gb:AAG56825.1; AE005406_4 (AE005406) putative nucleolar proteins; E=2e-21 pir:C64945; probable rRNA methylase yebU - Escherichia coli -----; E=5e-21 COG: yebU_1; COG0144 tRNA and rRNA cytosine-C5-methylases; E=5e-22 PFAM: PF01189; NOL1/NOP2/sun family; E=1.1e-24; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.622
uroD
Uroporphyrinogen III synthase, uroporhyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
    0.581
mesJ
Cell cycle protein homolog mesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
   
  
 0.580
RB7801
Hypothetical protein.
       0.572
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.545
RB13032
Conserved hypothetical protein-putative permease; PMID: 9384377 best DB hits: BLAST: pir:E69759; hypothetical protein ycgR - Bacillus subtilis -----; E=5e-06 ddbj:BAB05237.1; (AP001512) BH1518~unknown conserved protein; E=2e-04 pir:H70420; conserved hypothetical protein aq_1388 - Aquifex; E=6e-04 COG: BS_ycgR; COG0701 Predicted permeases; E=4e-07.
   
    0.542
spoU
spoU rRNA Methylase family; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
 
  
 0.516
gidA
Glucose inhibited division protein A (GIDA); NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
  
 0.495
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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