node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RB7881 | RB7886 | RB7881 | RB7886 | Hypothetical protein. | Hypothetical protein-putative transmembrane protein. | 0.572 |
RB7881 | mutL | RB7881 | RB7883 | Hypothetical protein. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.572 |
RB7881 | pdxA | RB7881 | RB7885 | Hypothetical protein. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.572 |
RB7886 | RB7881 | RB7886 | RB7881 | Hypothetical protein-putative transmembrane protein. | Hypothetical protein. | 0.572 |
RB7886 | mutL | RB7886 | RB7883 | Hypothetical protein-putative transmembrane protein. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.773 |
RB7886 | pdxA | RB7886 | RB7885 | Hypothetical protein-putative transmembrane protein. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.773 |
gyrB-2 | pdxA | RB3466 | RB7885 | DNA gyrase subunit B; PMID: 8863738 best DB hits: BLAST: pir:JC4960; DNA topoisomerase (ATP-hydrolyzing) (EC 5.99.1.3) B -; E=1e-140 swissprot:P77993; GYRB_THEMA DNA GYRASE SUBUNIT B (TOPOISOMERASE; E=1e-140 gb:AAG21374.1; AF288224_1 (AF288224) DNA Gyrase B subunit; E=1e-136 COG: TM0833; COG0187 DNA gyrase (topoisomerase II) B subunit; E=1e-141 PFAM: PF02518; Histidine kinase-, DNA gyrase B; E=2.1e-26 PF00204; DNA topoisomerase II (N-termina; E=1.3e-54 PF01751; Toprim domain; E=2.9e-10. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.566 |
gyrB-2 | secD | RB3466 | RB4633 | DNA gyrase subunit B; PMID: 8863738 best DB hits: BLAST: pir:JC4960; DNA topoisomerase (ATP-hydrolyzing) (EC 5.99.1.3) B -; E=1e-140 swissprot:P77993; GYRB_THEMA DNA GYRASE SUBUNIT B (TOPOISOMERASE; E=1e-140 gb:AAG21374.1; AF288224_1 (AF288224) DNA Gyrase B subunit; E=1e-136 COG: TM0833; COG0187 DNA gyrase (topoisomerase II) B subunit; E=1e-141 PFAM: PF02518; Histidine kinase-, DNA gyrase B; E=2.1e-26 PF00204; DNA topoisomerase II (N-termina; E=1.3e-54 PF01751; Toprim domain; E=2.9e-10. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.421 |
ksgA | pdxA | RB12377 | RB7885 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.620 |
mutL | RB7881 | RB7883 | RB7881 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Hypothetical protein. | 0.572 |
mutL | RB7886 | RB7883 | RB7886 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Hypothetical protein-putative transmembrane protein. | 0.773 |
mutL | pdxA | RB7883 | RB7885 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.784 |
mutL | secD | RB7883 | RB4633 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.464 |
pdxA | RB7881 | RB7885 | RB7881 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Hypothetical protein. | 0.572 |
pdxA | RB7886 | RB7885 | RB7886 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Hypothetical protein-putative transmembrane protein. | 0.773 |
pdxA | gyrB-2 | RB7885 | RB3466 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | DNA gyrase subunit B; PMID: 8863738 best DB hits: BLAST: pir:JC4960; DNA topoisomerase (ATP-hydrolyzing) (EC 5.99.1.3) B -; E=1e-140 swissprot:P77993; GYRB_THEMA DNA GYRASE SUBUNIT B (TOPOISOMERASE; E=1e-140 gb:AAG21374.1; AF288224_1 (AF288224) DNA Gyrase B subunit; E=1e-136 COG: TM0833; COG0187 DNA gyrase (topoisomerase II) B subunit; E=1e-141 PFAM: PF02518; Histidine kinase-, DNA gyrase B; E=2.1e-26 PF00204; DNA topoisomerase II (N-termina; E=1.3e-54 PF01751; Toprim domain; E=2.9e-10. | 0.566 |
pdxA | ksgA | RB7885 | RB12377 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.620 |
pdxA | mutL | RB7885 | RB7883 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.784 |
pdxA | pdxJ | RB7885 | RB536 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.927 |
pdxA | ribA | RB7885 | RB12480 | Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.480 |