STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pkn2PMID: 7774814 best DB hits: BLAST: pir:B70936; probable serinethreonine-specific protein kinase (EC; E=3e-31 embl:CAA18685.1; (AL022602) putative serinethreonine protein; E=5e-31 ddbj:BAB06223.1; (AP001515) serinethreonine protein kinase; E=6e-30 COG: Rv2176; COG0515 Serine/threonine protein kinases; E=3e-32 PFAM: PF00069; Protein kinase domain; E=1.2e-49. (513 aa)    
Predicted Functional Partners:
Pph1
Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09.
 
   0.803
RB3245
Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09.
  
   0.801
sigW-3
Probable ECF sigma factor; Best DB hits: BLAST: embl:CAC17654.1; (AL450450) putative ECF sigma factor; E=0.003 ddbj:BAB03982.1; (AP001507) RNA polymerase ECF-type sigma; E=0.005 swissprot:Q45585; SIGW_BACSU RNA POLYMERASE SIGMA FACTOR SIGW; E=0.005 COG: BH0263; COG1595 DNA-directed RNA polymerase specialized sigma; E=4e-04 PFAM: PF00776; Sigma-70 factor (ECF subfamily); E=5.2e-10.
   
   0.784
RB8557
Best DB hits: BLAST: pir:G82380; hypothetical protein VCA1075 [imported] - Vibrio; E=0.50.
       0.773
RB8552
Hypothetical protein-signal peptide and transmembrane prediction.
       0.561
RB10333
Protein kinase homolog; Best DB hits: BLAST: pir:T42076; protein kinase homolog - Streptomyces coelicolor -----; E=5e-18 pir:T42077; protein kinase homolog - Streptomyces coelicolor -----; E=1e-16 pir:T35491; probable serinethreonine-specific protein kinase pkaF -; E=1e-16 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=3e-15 PFAM: PF00069; Protein kinase domain; E=3.2e-06.
  
   
0.483
pknB-4
Probable serine/threonine-protein kinase; PMID: 8969512 best DB hits: BLAST: embl:CAA18685.1; (AL022602) putative serinethreonine protein; E=3e-23 pir:B70936; probable serinethreonine-specific protein kinase (EC; E=2e-22 swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=6e-22 COG: Rv2176; COG0515 Serine/threonine protein kinases; E=2e-23 PFAM: PF00069; Protein kinase domain; E=9.4e-41.
  
   
0.479
pknB-7
Serine/threonine kinase Pkn10; PMID: 99426839 best DB hits: BLAST: gb:AAF80365.1; AF159160_1 (AF159160) serinethreonine kinase Pkn10; E=6e-50 swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=3e-46 swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=7e-44 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=7e-45 PFAM: PF00069; Protein kinase domain; E=1.6e-64.
  
   
0.467
pknB-2
Probable serine/threonine-protein kinase pknB; PMID: 835671 best DB hits: BLAST: swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=3e-34 swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=5e-33 pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=9e-32 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=5e-34 PFAM: PF00069; Protein kinase domain; E=1.3e-46 PF00400; WD domain, G-beta repeat; E=0.00029.
  
   
0.464
pknB
Probable serine/threonine-protein kinase pknB; Best DB hits: BLAST: swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=9e-38 pir:H69878; probable protein kinase (EC 2.7.1.-) yloP - Bacillus; E=3e-37 ddbj:BAB06223.1; (AP001515) serinethreonine protein kinase; E=7e-37 COG: BS_yloP_1; COG0515 Serine/threonine protein kinases; E=2e-38 PFAM: PF00069; Protein kinase domain; E=2.1e-52.
  
  
0.463
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.