STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgmPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (543 aa)    
Predicted Functional Partners:
eno
Enolase (2-phosphoglycerate dehydratase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.992
pgk
Phosphoglycerate kinase; PMID: 8021172 best DB hits: BLAST: swissprot:P40924; PGK_BACSU PHOSPHOGLYCERATE KINASE ----- pir:; E=3e-96 swissprot:O52632; PGK_CLOAB PHOSPHOGLYCERATE KINASE -----gb:; E=4e-96 swissprot:P29409; PGKH_SPIOL PHOSPHOGLYCERATE KINASE, CHLOROPLAST; E=2e-93 COG: BS_pgk; COG0126 3-phosphoglycerate kinase; E=3e-97 PFAM: PF00162; Phosphoglycerate kinase; E=8.3e-186; Belongs to the phosphoglycerate kinase family.
  
 
 0.989
grp
RNA-binding protein; PMID: 7541909 best DB hits: BLAST: ddbj:BAA08402.1; (D49424) RNA-binding protein [Anabaena; E=4e-16 pir:S58673; RNA-binding protein RbpC - Anabaena variabilis; E=4e-16 pir:S77263; RNA-binding protein ssr1480 - Synechocystis sp. (strain; E=1e-15 COG: ssr1480; COG0724 RNA-binding proteins (RRM domain); E=1e-16 PFAM: PF00076; RNA recognition motif. (a.k.a. RRM,; E=2.9e-31.
   
 0.973
bcpC
Best DB hits: BLAST: pir:D69154; probable phosphonopyruvate decarboxylase (EC 4.1.1.-) 1; E=3e-86 gb:AAB89821.1; (AE001005) phosphonopyruvate decarboxylase; E=2e-64 pir:D69079; phosphonopyruvate decarboxylase (EC 4.1.1.-) -; E=7e-48 COG: MTH418; COG1015 Phosphopentomutase/predicted phosphoglycerate mutase; E=3e-87 MTH1591; COG1015 Phosphopentomutase/predicted phosphoglycerate; E=7e-49 MJ1612; COG1015 Phosphopentomutase/predicted phosphoglycerate mutase; E=2e-47 PFAM: PF02023; SCAN domain; E=0.75 PF01676; Metalloenzyme superfamily; E=4.3e-29.
    
 0.919
RB6467
PMID: 9537320 best DB hits: BLAST: pir:A70471; phosphoglycerate mutase 1 - Aquifex aeolicus -----; E=0.006 pir:G69831; phosphoglycerate mutase (glycolysis) homolog yhfR -; E=0.012 embl:CAA99510.1; (Z75191) ORF YOR283w [Saccharomyces; E=0.021 COG: aq_1990; COG0406 Phosphoglycerate; E=6e-04 BS_yhfR; COG0406 Phosphoglycerate mutase/fructose-2,6-bisphosphatase; E=0.001 YOR283w; COG0406 Phosphoglycerate; E=0.002 PFAM: PF00300; Phosphoglycerate mutase family; E=3.9e-05.
     
 0.911
serA-2
Phosphoglycerate dehydrogenase; Best DB hits: BLAST: gb:AAB90429.1; (AE001048) phosphoglycerate dehydrogenase (serA); E=2e-97 ddbj:BAB05321.1; (AP001512) D-3-phosphoglycerate dehydrogenase; E=2e-94 swissprot:P73821; SERA_SYNY3 D-3-PHOSPHOGLYCERATE DEHYDROGENASE; E=2e-92 COG: AF0813; COG0111 Phosphoglycerate dehydrogenase and related; E=2e-98 PFAM: PF00389; D-isomer specific 2-hydroxyacid; E=5.3e-11 PF01408; Oxidoreductase family, NAD-bindi; E=0.15 PF02826; D-isomer specific 2-hydroxyacid; E=1.2e-88.
     
 0.905
RB10787
Conserved hypothetical protein-putative glycerate kinase; Best DB hits: BLAST: pir:A72236; hypothetical protein TM1585 - Thermotoga maritima; E=8e-33 pir:B71162; hypothetical protein PH0495 - Pyrococcus horikoshii; E=6e-30 swissprot:Q44472; TUD4_AGRVI PUTATIVE HYDROXYPYRUVATE REDUCTASE; E=5e-29 COG: TM1585; COG2379 Putative glycerate kinase; E=8e-34.
    
  0.902
pgi
Glucose-6-phosphate isomerase; PMID: 2549364 best DB hits: BLAST: swissprot:P80860; G6PI_BACSU GLUCOSE-6-PHOSPHATE ISOMERASE (GPI); E=6e-53 ddbj:BAB07062.1; (AP001518) glucose-6-phosphate isomerase; E=4e-52 pir:S15937; glucose-6-phosphate isomerase (EC 5.3.1.9) - Bacillus; E=5e-52 COG: BS_pgi; COG0166 Glucose-6-phosphate isomerase; E=6e-54 PFAM: PF00342; Phosphoglucose isomerase; E=6.8e-31.
  
 
 0.895
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.883
fba
Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.869
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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