STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB9404Hypothetical zinc protease; Best DB hits: BLAST: swissprot:O33324; YR82_MYCTU HYPOTHETICAL ZINC PROTEASE RV2782C; E=3e-47 swissprot:O32965; YR82_MYCLE HYPOTHETICAL ZINC PROTEASE MLCB22.26C; E=7e-44 pir:H75263; probable zinc proteinase - Deinococcus radiodurans; E=9e-43 COG: Rv2782c; COG0612 Predicted Zn-dependent peptidases; E=3e-48 PFAM: PF00675; Insulinase (Peptidase family M1; E=4.8e-38; Belongs to the peptidase M16 family. (420 aa)    
Predicted Functional Partners:
RB4417
Cytochrome-c oxidase chain II/c precursor; PMID: 89231697 PMID: 91161592 best DB hits: BLAST: pir:A23711; cytochrome-c oxidase (EC 1.9.3.1) chain IIc precursor -; E=3e-42 swissprot:Q04441; COX2_BACFI CYTOCHROME C OXIDASE POLYPEPTIDE II; E=5e-38 ddbj:BAB06334.1; (AP001516) cytochrome caa3 oxidase (subunit II); E=2e-35 COG: BH2615_1; COG1622 Heme/copper-type cytochrome/quinol oxidases,; E=2e-21 XF1390; COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit; E=1e-14 slr1136; COG1622 Heme/copper-type cytochrome/quinol oxidases,; E=3e-14 PFAM: PF00116; Cytochrome C oxidase subunit II, [...]
  
 0.997
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
  
 
 0.894
RB2103
Acyl-CoA synthetase; PMID: 9634230 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-101 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=4e-96 gb:AAG02359.1; AF210249_18 (AF210249) peptide synthetase NRPS5-4-3; E=7e-93 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=4e-97 Rv3826; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-82 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=9e-19 PFAM: PF00501; AMP-binding enzyme; E=1.7e-07 PF00550; Phosphopantetheine attachment sit; [...]
   
 
 0.885
RB9402
Hypothetical zinc protease; PMID: 9634230 best DB hits: BLAST: pir:A75264; hypothetical protein - Deinococcus radiodurans (strain; E=2e-36 gb:AAF78805.1; (U33883) mitochondrial processing peptidase-like; E=1e-35 swissprot:O86835; YA12_STRCO HYPOTHETICAL ZINC PROTEASE SC9A10.02; E=7e-26 COG: DR2516; COG0612 Predicted Zn-dependent peptidases; E=2e-37.
 
    
0.863
nuoM
PMID: 7690854 best DB hits: BLAST: pir:H81796; NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain M; E=1e-15 pir:E81220; NADH dehydrogenase I, M chain NMB0258 [imported] -; E=4e-15 swissprot:Q9ZCG0; NUOM_RICPR NADH DEHYDROGENASE I CHAIN M; E=3e-14 COG: NMB0258; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); E=4e-16 PH1431; COG0651 Formate hydrogenlyase subunit 3; E=6e-13 HP1272; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); E=3e-12 PFAM: PF00361; NADH-Ubiquinone/plastoquinone (co; E=2e-07.
    
 
 0.819
RB9405
Hypothetical protein.
       0.773
atpD
Probable ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
   
 
 0.680
atpA
Protein ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 
 0.632
atpA-2
F0F1-ATPase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 
 0.632
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
 
 0.599
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.