node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pph1 | RB5876 | RB8362 | RB5876 | Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09. | Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:P54737; PKN5_MYXXA SERINETHREONINE-PROTEIN KINASE PKN5; E=3e-09 gb:AAF87930.1; AF163841_9 (AF163841) putative serinethreonine; E=4e-09 swissprot:P54738; PKN6_MYXXA SERINETHREONINE-PROTEIN KINASE PKN6; E=1e-07 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=1e-07 PFAM: PF00069; Protein kinase domain; E=3.8e-08 PF01130; CD36 family; E=0.61. | 0.690 |
Pph1 | pkn2-2 | RB8362 | RB9435 | Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09. | Putative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=9e-43 swissprot:P54736; PKN2_MYXXA SERINETHREONINE-PROTEIN KINASE PKN2; E=4e-39 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=2e-38 COG: Rv2088; COG0515 Serine/threonine protein kinases; E=2e-39 PFAM: PF00069; Protein kinase domain; E=1.6e-54. | 0.816 |
RB3245 | RB5876 | RB3245 | RB5876 | Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09. | Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:P54737; PKN5_MYXXA SERINETHREONINE-PROTEIN KINASE PKN5; E=3e-09 gb:AAF87930.1; AF163841_9 (AF163841) putative serinethreonine; E=4e-09 swissprot:P54738; PKN6_MYXXA SERINETHREONINE-PROTEIN KINASE PKN6; E=1e-07 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=1e-07 PFAM: PF00069; Protein kinase domain; E=3.8e-08 PF01130; CD36 family; E=0.61. | 0.685 |
RB3245 | pkn2-2 | RB3245 | RB9435 | Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09. | Putative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=9e-43 swissprot:P54736; PKN2_MYXXA SERINETHREONINE-PROTEIN KINASE PKN2; E=4e-39 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=2e-38 COG: Rv2088; COG0515 Serine/threonine protein kinases; E=2e-39 PFAM: PF00069; Protein kinase domain; E=1.6e-54. | 0.816 |
RB4632 | RB7093 | RB4632 | RB7093 | Conserved hypothetical protein-putative preprotein translocase subunit yajC; Best DB hits: BLAST: ddbj:BAB04948.1; (AP001511) BH1229~unknown conserved protein; E=3e-04 gb:AAK02312.1; (AE006057) YajC [Pasteurella multocida]; E=3e-04 pir:D72325; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-04 COG: BH1229; COG1862 Preprotein translocase subunit YajC; E=3e-05 PFAM: PF02699; Uncharacterized secreted proteins, Y; E=5.5e-17. | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.418 |
RB4632 | pkn2-2 | RB4632 | RB9435 | Conserved hypothetical protein-putative preprotein translocase subunit yajC; Best DB hits: BLAST: ddbj:BAB04948.1; (AP001511) BH1229~unknown conserved protein; E=3e-04 gb:AAK02312.1; (AE006057) YajC [Pasteurella multocida]; E=3e-04 pir:D72325; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-04 COG: BH1229; COG1862 Preprotein translocase subunit YajC; E=3e-05 PFAM: PF02699; Uncharacterized secreted proteins, Y; E=5.5e-17. | Putative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=9e-43 swissprot:P54736; PKN2_MYXXA SERINETHREONINE-PROTEIN KINASE PKN2; E=4e-39 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=2e-38 COG: Rv2088; COG0515 Serine/threonine protein kinases; E=2e-39 PFAM: PF00069; Protein kinase domain; E=1.6e-54. | 0.641 |
RB4632 | secD | RB4632 | RB4633 | Conserved hypothetical protein-putative preprotein translocase subunit yajC; Best DB hits: BLAST: ddbj:BAB04948.1; (AP001511) BH1229~unknown conserved protein; E=3e-04 gb:AAK02312.1; (AE006057) YajC [Pasteurella multocida]; E=3e-04 pir:D72325; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-04 COG: BH1229; COG1862 Preprotein translocase subunit YajC; E=3e-05 PFAM: PF02699; Uncharacterized secreted proteins, Y; E=5.5e-17. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.970 |
RB4632 | secE | RB4632 | RB7897 | Conserved hypothetical protein-putative preprotein translocase subunit yajC; Best DB hits: BLAST: ddbj:BAB04948.1; (AP001511) BH1229~unknown conserved protein; E=3e-04 gb:AAK02312.1; (AE006057) YajC [Pasteurella multocida]; E=3e-04 pir:D72325; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-04 COG: BH1229; COG1862 Preprotein translocase subunit YajC; E=3e-05 PFAM: PF02699; Uncharacterized secreted proteins, Y; E=5.5e-17. | Hypothetical protein-putative SecE protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.513 |
RB4632 | secY | RB4632 | RB7866 | Conserved hypothetical protein-putative preprotein translocase subunit yajC; Best DB hits: BLAST: ddbj:BAB04948.1; (AP001511) BH1229~unknown conserved protein; E=3e-04 gb:AAK02312.1; (AE006057) YajC [Pasteurella multocida]; E=3e-04 pir:D72325; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-04 COG: BH1229; COG1862 Preprotein translocase subunit YajC; E=3e-05 PFAM: PF02699; Uncharacterized secreted proteins, Y; E=5.5e-17. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.438 |
RB5876 | Pph1 | RB5876 | RB8362 | Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:P54737; PKN5_MYXXA SERINETHREONINE-PROTEIN KINASE PKN5; E=3e-09 gb:AAF87930.1; AF163841_9 (AF163841) putative serinethreonine; E=4e-09 swissprot:P54738; PKN6_MYXXA SERINETHREONINE-PROTEIN KINASE PKN6; E=1e-07 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=1e-07 PFAM: PF00069; Protein kinase domain; E=3.8e-08 PF01130; CD36 family; E=0.61. | Probable protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=9e-32 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=4e-28 pir:H75265; conserved hypothetical protein - Deinococcus radiodurans; E=5e-28 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-29 PFAM: PF00481; Protein phosphatase 2C; E=4.9e-09. | 0.690 |
RB5876 | RB3245 | RB5876 | RB3245 | Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:P54737; PKN5_MYXXA SERINETHREONINE-PROTEIN KINASE PKN5; E=3e-09 gb:AAF87930.1; AF163841_9 (AF163841) putative serinethreonine; E=4e-09 swissprot:P54738; PKN6_MYXXA SERINETHREONINE-PROTEIN KINASE PKN6; E=1e-07 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=1e-07 PFAM: PF00069; Protein kinase domain; E=3.8e-08 PF01130; CD36 family; E=0.61. | Protein phosphatase 1; PMID: 11298281 best DB hits: BLAST: gb:AAF81068.1; AF223364_3 (AF223364) protein phosphatase 1; E=3e-27 pir:E71538; hypothetical protein CT259 - Chlamydia trachomatis; E=5e-26 embl:CAA10712.1; (AJ132604) pppL protein [Lactococcus lactis]; E=2e-25 COG: CT259; COG0631 Protein serine/threonine phosphatases; E=4e-27 PFAM: PF00481; Protein phosphatase 2C; E=1.2e-09. | 0.685 |
RB5876 | pkn2-2 | RB5876 | RB9435 | Probable serine/threonine-protein kinase; PMID: 7768349 best DB hits: BLAST: swissprot:P54737; PKN5_MYXXA SERINETHREONINE-PROTEIN KINASE PKN5; E=3e-09 gb:AAF87930.1; AF163841_9 (AF163841) putative serinethreonine; E=4e-09 swissprot:P54738; PKN6_MYXXA SERINETHREONINE-PROTEIN KINASE PKN6; E=1e-07 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=1e-07 PFAM: PF00069; Protein kinase domain; E=3.8e-08 PF01130; CD36 family; E=0.61. | Putative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=9e-43 swissprot:P54736; PKN2_MYXXA SERINETHREONINE-PROTEIN KINASE PKN2; E=4e-39 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=2e-38 COG: Rv2088; COG0515 Serine/threonine protein kinases; E=2e-39 PFAM: PF00069; Protein kinase domain; E=1.6e-54. | 0.727 |
RB7093 | RB4632 | RB7093 | RB4632 | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Conserved hypothetical protein-putative preprotein translocase subunit yajC; Best DB hits: BLAST: ddbj:BAB04948.1; (AP001511) BH1229~unknown conserved protein; E=3e-04 gb:AAK02312.1; (AE006057) YajC [Pasteurella multocida]; E=3e-04 pir:D72325; hypothetical protein - Thermotoga maritima (strain MSB8); E=5e-04 COG: BH1229; COG1862 Preprotein translocase subunit YajC; E=3e-05 PFAM: PF02699; Uncharacterized secreted proteins, Y; E=5.5e-17. | 0.418 |
RB7093 | pkn2-2 | RB7093 | RB9435 | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Putative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=9e-43 swissprot:P54736; PKN2_MYXXA SERINETHREONINE-PROTEIN KINASE PKN2; E=4e-39 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=2e-38 COG: Rv2088; COG0515 Serine/threonine protein kinases; E=2e-39 PFAM: PF00069; Protein kinase domain; E=1.6e-54. | 0.876 |
RB7093 | secD | RB7093 | RB4633 | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.970 |
RB7093 | secE | RB7093 | RB7897 | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein-putative SecE protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.978 |
RB7093 | secY | RB7093 | RB7866 | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.918 |
RB7093 | yidC | RB7093 | RB8240 | Hypothetical protein-transmembrane prediction; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 60 kDa inner-membrane protein homolog-putative part of a protein secretion system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). | 0.918 |
alaS | pkn2-2 | RB8543 | RB9435 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative serine/threonine-protein kinase; PMID: 7774814 best DB hits: BLAST: embl:CAB94054.1; (AL358672) putative serinethreonine-protein; E=9e-43 swissprot:P54736; PKN2_MYXXA SERINETHREONINE-PROTEIN KINASE PKN2; E=4e-39 swissprot:Q10697; PKNJ_MYCTU PROBABLE SERINETHREONINE-PROTEIN; E=2e-38 COG: Rv2088; COG0515 Serine/threonine protein kinases; E=2e-39 PFAM: PF00069; Protein kinase domain; E=1.6e-54. | 0.684 |
alaS | secD | RB8543 | RB4633 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.816 |