node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR_0168 | DR_0169 | DR_0168 | DR_0169 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
DR_0168 | DR_0170 | DR_0168 | DR_0170 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.86; identified by sequence similarity; putative. | 0.999 |
DR_0168 | folE | DR_0168 | DR_0036 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase I; Similar to SP:Q54769 percent identity: 77.22; identified by sequence similarity; putative. | 0.989 |
DR_0168 | ribBA | DR_0168 | DR_0155 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.451 |
DR_0169 | DR_0168 | DR_0169 | DR_0168 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
DR_0169 | DR_0170 | DR_0169 | DR_0170 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.86; identified by sequence similarity; putative. | 0.999 |
DR_0169 | folE | DR_0169 | DR_0036 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; Similar to SP:Q54769 percent identity: 77.22; identified by sequence similarity; putative. | 0.986 |
DR_0169 | ribBA | DR_0169 | DR_0155 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.458 |
DR_0170 | DR_0168 | DR_0170 | DR_0168 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.86; identified by sequence similarity; putative. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
DR_0170 | DR_0169 | DR_0170 | DR_0169 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.86; identified by sequence similarity; putative. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
DR_0170 | folE | DR_0170 | DR_0036 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.86; identified by sequence similarity; putative. | GTP cyclohydrolase I; Similar to SP:Q54769 percent identity: 77.22; identified by sequence similarity; putative. | 0.998 |
DR_0170 | ribBA | DR_0170 | DR_0155 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801 percent identity: 56.86; identified by sequence similarity; putative. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.514 |
DR_1838 | DR_2635 | DR_1838 | DR_2635 | GTP pyrophosphokinase; Similar to GB:X72832 SP:Q54089 percent identity: 62.15; identified by sequence similarity; putative. | Pyruvate kinase; Similar to PID:598097 SP:Q46078 percent identity: 63.38; identified by sequence similarity; putative; Belongs to the pyruvate kinase family. | 0.923 |
DR_1838 | folE | DR_1838 | DR_0036 | GTP pyrophosphokinase; Similar to GB:X72832 SP:Q54089 percent identity: 62.15; identified by sequence similarity; putative. | GTP cyclohydrolase I; Similar to SP:Q54769 percent identity: 77.22; identified by sequence similarity; putative. | 0.801 |
DR_1838 | ndk | DR_1838 | DR_2499 | GTP pyrophosphokinase; Similar to GB:X72832 SP:Q54089 percent identity: 62.15; identified by sequence similarity; putative. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.917 |
DR_1838 | ribBA | DR_1838 | DR_0155 | GTP pyrophosphokinase; Similar to GB:X72832 SP:Q54089 percent identity: 62.15; identified by sequence similarity; putative. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.843 |
DR_2635 | DR_1838 | DR_2635 | DR_1838 | Pyruvate kinase; Similar to PID:598097 SP:Q46078 percent identity: 63.38; identified by sequence similarity; putative; Belongs to the pyruvate kinase family. | GTP pyrophosphokinase; Similar to GB:X72832 SP:Q54089 percent identity: 62.15; identified by sequence similarity; putative. | 0.923 |
DR_2635 | folE | DR_2635 | DR_0036 | Pyruvate kinase; Similar to PID:598097 SP:Q46078 percent identity: 63.38; identified by sequence similarity; putative; Belongs to the pyruvate kinase family. | GTP cyclohydrolase I; Similar to SP:Q54769 percent identity: 77.22; identified by sequence similarity; putative. | 0.808 |
DR_2635 | glyA | DR_2635 | DR_0038 | Pyruvate kinase; Similar to PID:598097 SP:Q46078 percent identity: 63.38; identified by sequence similarity; putative; Belongs to the pyruvate kinase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.484 |
DR_2635 | ndk | DR_2635 | DR_2499 | Pyruvate kinase; Similar to PID:598097 SP:Q46078 percent identity: 63.38; identified by sequence similarity; putative; Belongs to the pyruvate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.910 |