STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdRConserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (157 aa)    
Predicted Functional Partners:
DR_0088
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to GB:AL009126 percent identity: 49.61; identified by sequence similarity; putative.
       0.843
argR
Arginine repressor/activator; Regulates arginine biosynthesis genes.
      
 0.842
nadE
NH3-dependent NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.800
DR_0153
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.768
DR_0090
Conserved hypothetical protein; Similar to PID:577591 percent identity: 54.49; identified by sequence similarity; putative.
  
    0.648
DR_0092
MutT/nudix family protein; Similar to SP:P54570 PID:1303984 GB:AL009126 percent identity: 47.27; identified by sequence similarity; putative.
     
 0.644
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
     
 0.641
DR_0089
Conserved hypothetical protein; Similar to PID:1653794 percent identity: 51.55; identified by sequence similarity; putative.
       0.636
DR_0091
Conserved hypothetical protein; Similar to PID:1653202 percent identity: 46.27; identified by sequence similarity; putative.
       0.636
DR_0093
Phytoene dehydrogenase, putative; Similar to PID:1001734 PID:1001724 percent identity: 54.72; identified by sequence similarity; putative.
       0.636
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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