STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Similar to GB:D26562 SP:P23893 GB:X53696 PID:41621 PID:473813 percent identity: 68.94; identified by sequence similarity; putative. (455 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.996
DR_2160
Delta-aminolevulinic acid dehydratase; Similar to GB:X70434 percent identity: 74.77; identified by sequence similarity; putative; Belongs to the ALAD family.
 
 
 0.992
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.949
DR_1945
Malonyl CoA-acyl carrier protein transacylase; Similar to GB:M87040 SP:P25715 GB:Z11565 PID:145887 PID:41364 percent identity: 63.37; identified by sequence similarity; putative.
    
 0.915
DR_A0011
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Similar to GB:D28503 PID:460693 percent identity: 56.88; identified by sequence similarity; putative.
 
  
 0.865
DR_0556
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 59.85; identified by sequence similarity; putative.
       0.843
DR_0554
Hypothetical protein; Identified by Glimmer2; putative.
       0.688
DR_1941
3-oxoacyl-acyl carrier protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.620
DR_0786
uroporphyrinogen-III synthase, putative; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.610
DR_0183
Glutamate synthase, large subunit; Similar to PID:1339950 percent identity: 71.96; identified by sequence similarity; putative.
     
 0.598
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.