STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (330 aa)    
Predicted Functional Partners:
DR_0557
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.922
trpS2
tryptophanyl-tRNA synthetase; Catalyzes the formation of 5'adenyl-Trp and tRNA(Trp) but with 5-fold less activity than TrpRS. Increases the solubility of the nitric oxide synthase oxygenase (nos), as well as its affinity for substrate L-arginine and its nitric-oxide synthase activity. The complex between trpS2 and nos catalyzes the regioselective nitration of tryptophan at the 4-position.
  
  
 
0.915
leuS
leucyl-tRNA synthetase; Similar to PID:1652380 percent identity: 64.42; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.791
potA
Spermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
      
 0.751
lysK
Succinyl-diaminopimelate desuccinylase, putative; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
      
 0.739
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
 
 0.691
pheS
phenylalanyl-tRNA synthetase, alpha subunit; Similar to SP:P27001 PID:48251 PID:48254 percent identity: 76.11; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
  
 0.612
lepA
GTP-binding elongation factor family protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
  
 0.599
pheT
phenylalanyl-tRNA synthetase, beta subunit; Similar to SP:P27002 PID:48252 PID:48255 percent identity: 59.16; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.596
argS
arginyl-tRNA synthetase; Similar to GB:Pyro_h percent identity: 62.62; identified by sequence similarity; putative.
  
  
 0.584
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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