node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR_0130 | DR_1368 | DR_0130 | DR_1368 | Coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.550 |
DR_0130 | rlmN | DR_0130 | DR_0936 | Coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.736 |
DR_0379 | DR_1368 | DR_0379 | DR_1368 | Outer membrane protein; Similar to PID:2231197 percent identity: 45.54; identified by sequence similarity; putative. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.526 |
DR_0379 | DR_1369 | DR_0379 | DR_1369 | Outer membrane protein; Similar to PID:2231197 percent identity: 45.54; identified by sequence similarity; putative. | Minicell-associated protein DivIVA; Similar to GP:1518680 percent identity: 47.99; identified by sequence similarity; putative. | 0.504 |
DR_1365 | DR_1368 | DR_1365 | DR_1368 | Aspartate kinase; Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 64.77; identified by sequence similarity; putative; Belongs to the aspartokinase family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.571 |
DR_1365 | DR_1369 | DR_1365 | DR_1369 | Aspartate kinase; Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 64.77; identified by sequence similarity; putative; Belongs to the aspartokinase family. | Minicell-associated protein DivIVA; Similar to GP:1518680 percent identity: 47.99; identified by sequence similarity; putative. | 0.545 |
DR_1365 | pdxS | DR_1365 | DR_1367 | Aspartate kinase; Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 64.77; identified by sequence similarity; putative; Belongs to the aspartokinase family. | Singlet oxygen resistance protein, putative; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.781 |
DR_1365 | pdxT | DR_1365 | DR_1366 | Aspartate kinase; Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 64.77; identified by sequence similarity; putative; Belongs to the aspartokinase family. | Amidotransferase HisH, putative; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.799 |
DR_1368 | DR_0130 | DR_1368 | DR_0130 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.550 |
DR_1368 | DR_0379 | DR_1368 | DR_0379 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Outer membrane protein; Similar to PID:2231197 percent identity: 45.54; identified by sequence similarity; putative. | 0.526 |
DR_1368 | DR_1365 | DR_1368 | DR_1365 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Aspartate kinase; Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 64.77; identified by sequence similarity; putative; Belongs to the aspartokinase family. | 0.571 |
DR_1368 | DR_1369 | DR_1368 | DR_1369 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Minicell-associated protein DivIVA; Similar to GP:1518680 percent identity: 47.99; identified by sequence similarity; putative. | 0.930 |
DR_1368 | DR_1966 | DR_1368 | DR_1966 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved hypothetical protein; Multicopper oxidase with polyphenol oxidase activity. | 0.640 |
DR_1368 | pdxS | DR_1368 | DR_1367 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Singlet oxygen resistance protein, putative; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.597 |
DR_1368 | pdxT | DR_1368 | DR_1366 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Amidotransferase HisH, putative; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.557 |
DR_1368 | pdxY | DR_1368 | DR_A0184 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.579 |
DR_1368 | proC | DR_1368 | DR_1522 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.526 |
DR_1368 | rlmN | DR_1368 | DR_0936 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.536 |
DR_1369 | DR_0379 | DR_1369 | DR_0379 | Minicell-associated protein DivIVA; Similar to GP:1518680 percent identity: 47.99; identified by sequence similarity; putative. | Outer membrane protein; Similar to PID:2231197 percent identity: 45.54; identified by sequence similarity; putative. | 0.504 |
DR_1369 | DR_1365 | DR_1369 | DR_1365 | Minicell-associated protein DivIVA; Similar to GP:1518680 percent identity: 47.99; identified by sequence similarity; putative. | Aspartate kinase; Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 64.77; identified by sequence similarity; putative; Belongs to the aspartokinase family. | 0.545 |