STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvsEUV damage endonuclease, putative; Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion. Belongs to the uve1/UvsE family. (326 aa)    
Predicted Functional Partners:
DR_2262
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.732
DR_1314
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 62.71; identified by sequence similarity; putative.
  
     0.718
DR_1820
Hypothetical protein; Identified by Glimmer2; putative.
       0.642
DR_1804
Conserved hypothetical protein; Similar to SP:P38522 GB:U00096 PID:1742120 PID:1742129 PID:1787557 percent identity: 50.63; identified by sequence similarity; putative.
  
     0.589
polA
DNA-directed DNA polymerase; A DNA polymerase, required for DNA repair after DNA damage induced by ionizing radiation (IR); this is not the major DNA polymerase. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synthesis requires both RecA and RadA, Pol III initiates DNA synthesis while both Pol I and Pol III are require [...]
     
 0.551
uvrA
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
      
 0.550
DR_A0364
Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to GB:AL009126 percent identity: 80.92; identified by sequence similarity; putative.
  
    0.550
DR_2484
WD-repeat family protein; Similar to GP:3426014 percent identity: 70.19; identified by sequence similarity; putative.
  
     0.514
DR_0856
DNA polymerase III, epsilon subunit, putative; Similar to GB:AE000657 percent identity: 51.01; identified by sequence similarity; putative.
       0.504
DR_1910
Thermoresistant gluconokinase; Similar to SP:P46859 PID:606372 GB:U00096 PID:1304070 PID:1789845 percent identity: 64.15; identified by sequence similarity; putative.
       0.504
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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