STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (432 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
DR_0813
1-pyrroline-5-carboxylate dehydrogenase; Similar to GB:X73124 SP:P39634 PID:414000 GB:AL009126 percent identity: 70.70; identified by sequence similarity; putative.
  
 
 0.907
DR_A0030
1-pyrroline-5-carboxylate dehydrogenase, putative; Similar to GB:X73124 SP:P39634 PID:414000 GB:AL009126 percent identity: 65.56; identified by sequence similarity; putative; Belongs to the aldehyde dehydrogenase family.
  
 
 0.907
DR_0183
Glutamate synthase, large subunit; Similar to PID:1339950 percent identity: 71.96; identified by sequence similarity; putative.
    
 0.884
DR_0451
Glutamine synthase; Similar to SP:P10656 PID:144818 percent identity: 73.52; identified by sequence similarity; putative; Belongs to the glutamine synthetase family.
    
 0.860
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
 0.852
DR_0980
Glutamate dehydrogenase, putative; Similar to GB:M65250 SP:P27346 PID:144820 percent identity: 71.60; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.816
DR_1718
Glutamate dehydrogenase; Similar to GB:M24021 SP:P15111 GB:X52093 PID:154085 percent identity: 83.10; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.816
GltD
Glutamate synthase, small subunit; Similar to GB:AL123456 percent identity: 72.27; identified by sequence similarity; putative.
    
 0.815
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.811
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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