STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dps1DNA-binding stress response protein, Dps family; Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). Both oligomeric forms of dps exhibit ferroxidase activity and DNA binding. Dodecameric dps is capable of Fe(2+) oxidation/mineralization. Only dimeric dps affords efficient DNA protection against hydroxyl radical-mediated cleavage. (207 aa)    
Predicted Functional Partners:
clpS
Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
  
 
 0.851
DR_2264
Zinc metallohydrolase, glyoxalase II family; Similar to PID:1208973 GB:U00096 SP:Q47677 PID:1552782 PID:1786406 percent identity: 53.78; identified by sequence similarity; putative.
       0.773
DR_2262
Hypothetical protein; Identified by Glimmer2; putative.
       0.704
DR_2242
Thiol-specific antioxidant protein, putative; Similar to PID:1001492 PID:1001510 percent identity: 64.39; identified by sequence similarity; putative.
  
  
 0.635
DR_2453
Cation-transporting ATPase; Similar to PID:1353678 percent identity: 72.61; identified by sequence similarity; putative.
  
  
 0.633
sodA
Superoxide dismutase (sodA), Mn family; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
 
  
 0.605
DR_A0214
Trp repressor binding protein WrbA, putative; Similar to GB:M99166 SP:P30849 PID:148264 GB:U00096 PID:1651499 percent identity: 54.36; identified by sequence similarity; putative; Belongs to the WrbA family.
  
  
 0.582
DR_0865
Ferric uptake regulation protein, putative; Similar to PID:1769570 percent identity: 44.96; identified by sequence similarity; putative; Belongs to the Fur family.
  
  
 0.554
hpf
Light-repressed protein A, putative; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
    0.539
DR_1538
Osmotically inducible protein C; Similar to SP:P23929 GB:X57433 PID:42181 GB:U00096 PID:1742412 percent identity: 63.04; identified by sequence similarity; putative.
  
  
 0.506
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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