node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR_0789 | DR_0873 | DR_0789 | DR_0873 | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | 0.834 |
DR_0789 | DR_1278 | DR_0789 | DR_1278 | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | 0.472 |
DR_0789 | DR_1452 | DR_0789 | DR_1452 | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Aminotransferase, class I; Similar to SP:Q08432 GB:S61781 PID:975351 PID:1934779 PID:1934787 percent identity: 54.03; identified by sequence similarity; putative. | 0.932 |
DR_0789 | DR_2186 | DR_0789 | DR_2186 | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-acetylhomoserine (thiol)-lyase/O-acetylserine (thiol)-lyase; Similar to PID:1526549 percent identity: 60.45; identified by sequence similarity; putative. | 0.841 |
DR_0789 | MetH | DR_0789 | DR_0966 | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.897 |
DR_0789 | luxS | DR_0789 | DR_2387 | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Conserved hypothetical protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD); Belongs to the LuxS family. | 0.879 |
DR_0873 | DR_0789 | DR_0873 | DR_0789 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.834 |
DR_0873 | DR_1278 | DR_0873 | DR_1278 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | 0.879 |
DR_0873 | DR_1452 | DR_0873 | DR_1452 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | Aminotransferase, class I; Similar to SP:Q08432 GB:S61781 PID:975351 PID:1934779 PID:1934787 percent identity: 54.03; identified by sequence similarity; putative. | 0.912 |
DR_0873 | DR_2186 | DR_0873 | DR_2186 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | O-acetylhomoserine (thiol)-lyase/O-acetylserine (thiol)-lyase; Similar to PID:1526549 percent identity: 60.45; identified by sequence similarity; putative. | 0.914 |
DR_0873 | MetH | DR_0873 | DR_0966 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.947 |
DR_0873 | ilvA | DR_0873 | DR_0567 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.811 |
DR_0873 | luxS | DR_0873 | DR_2387 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | Conserved hypothetical protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD); Belongs to the LuxS family. | 0.903 |
DR_0873 | thrB | DR_0873 | DR_2390 | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.808 |
DR_1278 | DR_0789 | DR_1278 | DR_0789 | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | O-acetylserine (thiol)-lyase; Similar to SP:Q43317 percent identity: 69.87; identified by sequence similarity; putative; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.472 |
DR_1278 | DR_0873 | DR_1278 | DR_0873 | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | O-acetylhomoserine (thiol)-lyase; Similar to SP:P50125 PID:633761 percent identity: 73.78; identified by sequence similarity; putative. | 0.879 |
DR_1278 | DR_1452 | DR_1278 | DR_1452 | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | Aminotransferase, class I; Similar to SP:Q08432 GB:S61781 PID:975351 PID:1934779 PID:1934787 percent identity: 54.03; identified by sequence similarity; putative. | 0.818 |
DR_1278 | DR_2186 | DR_1278 | DR_2186 | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | O-acetylhomoserine (thiol)-lyase/O-acetylserine (thiol)-lyase; Similar to PID:1526549 percent identity: 60.45; identified by sequence similarity; putative. | 0.874 |
DR_1278 | MetH | DR_1278 | DR_0966 | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.932 |
DR_1278 | ilvA | DR_1278 | DR_0567 | Homoserine dehydrogenase; Similar to SP:P08499 GB:Y00476 PID:297383 PID:40503 percent identity: 56.69; identified by sequence similarity; putative. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.548 |