STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
defPolypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (232 aa)    
Predicted Functional Partners:
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
 
 0.963
rplQ
Ribosomal protein L17; Binds to the 23S rRNA; Belongs to the bacterial ribosomal protein bL17 family.
  
   0.941
rplT
Ribosomal protein L20; Binds directly to 23S rRNA, probably serving to organize its structure; Belongs to the bacterial ribosomal protein bL20 family.
 
 
 0.936
rplV
Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
    
   0.935
rpsP
Ribosomal protein S16; Similar to PID:2149138 percent identity: 86.57; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family.
 
   0.924
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
 
 0.923
rpsO
Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
 
 
   0.922
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Probably changes conformation upon binding to the ribosome (maybe in particular due to interaction with L24, , exposing a hydrophobic crevice that is probably important for its chaperone activity.
  
 
 0.914
rpmA
Ribosomal protein L27; Binds the 5S and 23S rRNAs and also the tRNA in the P site; Belongs to the bacterial ribosomal protein bL27 family.
 
   0.909
rplI
Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family.
 
   0.907
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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